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Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Testosterone therapy increases bone density in older men with low testosterone levels.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Finasteride effectively treats baldness but may cause sexual side effects.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Targeting the skin's endocannabinoid system could help treat skin disorders.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Vitamin D and its receptor may help prevent skin cancer.

Tamoxifen effectively treats gynecomastia without causing impotence.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Baricitinib for severe alopecia areata is generally safe, with common side effects like infections and acne, and low rates of serious complications.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

People undergoing chemotherapy need better support and information to cope with hair loss.

Lespedeza cuneata extract may help treat enlarged prostate.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.