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The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Hair restoration can be achieved through non-surgical treatments like minoxidil, antiandrogens, phototherapy, and PRP procedures, or through surgical methods like hair transplantation. Continued treatment is needed to maintain results, and full results are visible after 12-18 months.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.

Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Finasteride effectively treats baldness but may cause sexual side effects.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Vitamin D receptor may help protect against UV-induced skin cancer.

Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.