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The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The pumpkin seed oil niosomes are promising for skin and hair treatments because they are stable and effectively deliver the oil.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Taking Saw palmetto and Pygeum africana can change the levels of certain steroids in urine, which could cause confusion in doping tests.

Bee pollen, green tea, essential oils, and various plant extracts improve skin and hair health.

Higher testosterone and DHT levels are not linked to urinary symptoms in men.

VB-1, a natural compound, may promote hair growth by enhancing a key cell growth pathway.

A mix of Polygonatum sibiricum and Nelumbinis semen may ease menopause symptoms with fewer side effects.

The follicular unit extraction method for hair transplants is a technique with benefits and drawbacks.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Metformin is less effective in men with early-onset hair loss.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Taking 5-α reductase inhibitors for prostate enlargement or hair loss does not significantly raise the risk of erectile dysfunction.

Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.