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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Testosterone may influence COVID-19 severity and outcomes.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

Mutations in certain receptors can cause diseases and offer new treatment options.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Finasteride effectively treats BPH and hair loss but may cause sexual side effects.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Low testosterone in men is a risk factor for a specific heart rhythm issue, and testosterone treatment may help prevent it.

Feeling younger can improve health and extend life.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

A new method was developed to make finasteride for treating hair loss.

Older men should openly discuss sexual health with doctors to improve their quality of life.

Antiandrogens can treat acne, hirsutism, and seborrhea by reducing sebum production and androgen action.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Young and adult hamsters both respond similarly to testosterone and finasteride treatments, but young hamsters aren't good for testing the inhibitory activity of a specific enzyme.

Androgen deprivation therapy might be better for preventing COVID-19 than treating it.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.

Dosing time affects finasteride's effectiveness and safety in rats.

Omega-6 fats in certain cells boost male hormone production.