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    Glossary Prostaglandins

    group of lipid compounds with hormone-like effects in the body

    Prostaglandins are a group of lipid compounds that are derived from fatty acids and have hormone-like effects in the body. They play a crucial role in various physiological processes, including inflammation, blood flow, the formation of blood clots, and the induction of labor. Prostaglandins are also involved in the regulation of hair growth and can influence conditions like alopecia.

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    1. Prostaglandin D <sub>2</sub> Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia Science Translational Medicine · 2012 · 205 citations
    2. Prostaglandin-Induced Hair Growth Survey of Ophthalmology · 2002 · 162 citations
    3. Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect Journal of Investigative Dermatology · 1997 · 81 citations
    4. Prostaglandin metabolism in human hair follicle Experimental Dermatology · 2007 · 65 citations
    5. Does prostaglandin D<sub>2</sub> hold the cure to male pattern baldness? Experimental Dermatology · 2014 · 57 citations
    6. Recent Progress in Prostaglandin F<sub>2</sub><i><sub>α</sub></i>Ethanolamide (Prostamide F<sub>2</sub><i><sub>α</sub></i>) Research and Therapeutics Pharmacological reviews · 2013 · 43 citations
    7. Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease Thrombosis Research · 2015 · 35 citations
    8. Increased levels of prostaglandin-like material in the canine blood during arterial hypotension produced by hydralazine, dihydralazine and minoxidil Naunyn-schmiedebergs Archives of Pharmacology · 1979 · 35 citations
    9. In silico prediction of prostaglandin D2 synthase inhibitors from herbal constituents for the treatment of hair loss Journal of Ethnopharmacology · 2015 · 30 citations
    10. After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and Wnts to Promote Regeneration Journal of Investigative Dermatology · 2017 · 27 citations
    11. Divergent proliferation patterns of distinct human hair follicle epithelial progenitor niches in situ and their differential responsiveness to prostaglandin D2 Scientific Reports · 2017 · 21 citations
    12. The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A Scientific Reports · 2020 · 20 citations
    13. Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase Journal of Lipid Research · 2013 · 20 citations
    14. Prostaglandin analogs for hair growth: Great Expectations Dermatology online journal · 2003 · 20 citations
    15. Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin Frontiers in Physiology · 2021 · 18 citations
    16. Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2018 · 18 citations
    17. HMGB1 promotes hair growth via the modulation of prostaglandin metabolism Scientific Reports · 2019 · 12 citations
    18. Expression of NAD+dependent 15-hydroxyprostaglandin dehydrogenase and protection of prostaglandins in human hair follicle Experimental Dermatology · 2008 · 11 citations
    19. Simultaneous determination of androgens and prostaglandins in human urine using ultra-high-performance liquid chromatography–tandem mass spectrometry Journal of Chromatography B · 2019 · 10 citations
    20. Computer-Aided Designing Peptide Inhibitors of Human Hematopoietic Prostaglandin D2 Synthase Combined Molecular Docking and Molecular Dynamics Simulation Molecules · 2023 · 9 citations
    21. Phosphodiesterase inhibitors and prostaglandin analogues in dermatology: A comprehensive review Dermatologic Therapy · 2020 · 9 citations
    22. Diphlorethohydroxycarmalol, Isolated from Ishige okamurae, Increases Prostaglandin E<sub>2</sub>through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes Biomolecules & therapeutics · 2012 · 9 citations
    23. Prostaglandins in androgenetic alopecia in 12 men and four female Journal of The European Academy of Dermatology and Venereology · 2019 · 8 citations
    24. No genetic support for a contribution of prostaglandins to the aetiology of androgenetic alopecia British Journal of Dermatology · 2013 · 7 citations
    25. The role of prostaglandins in androgenetic alopecia International Journal of Dermatology · 2021 · 4 citations
    26. Understanding Pattern Hair Loss—Hair Biology Impacted by Genes, Androgens, Prostaglandins and Epigenetic Factors Indian Journal of Plastic Surgery · 2021 · 3 citations
    27. Prostaglandins: Key players in immunomodulation of the nervous system Neural Regeneration Research · 2025 · 3 citations
    28. Eyelash Preservation During Chemotherapy and Topical Prostaglandin Therapy Archives of internal medicine · 2010 · 3 citations
    29. Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm Reproduction · 2021 · 2 citations
    30. Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (<i>Capra hircus</i>) Skin during Hair Follicle Development Animal Biotechnology · 2014 · 2 citations