46 citations,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
45 citations,
May 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
38 citations,
September 2019 in “Chinese Medical Journal” Using steroids can increase the risk of heart problems.
34 citations,
February 2018 in “Drug Design Development and Therapy” Bimatoprost is safe and effective for improving eyebrow hair.
31 citations,
September 2014 in “International Journal of Dermatology” Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.
30 citations,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
28 citations,
January 2018 in “Biochemical Society Transactions” Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
28 citations,
February 2016 in “F1000Research” Understanding glycans and enzymes that alter them is key to controlling hair growth.
20 citations,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
19 citations,
November 2011 Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
15 citations,
January 2015 in “Skin Pharmacology and Physiology” Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.
13 citations,
May 2021 in “Plants” The leaf extract of Leea indica may reduce inflammation, dissolve blood clots, and promote hair growth.
11 citations,
July 2020 in “International Journal of Ayurvedic Medicine” Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.
11 citations,
January 1998 in “Dermatology” Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.
9 citations,
January 2008 in “Acta histochemica et cytochemica” COX-2 levels change during the hair cycle and affect skin and hair growth.
8 citations,
February 2019 in “Journal of The European Academy of Dermatology and Venereology”
7 citations,
February 2018 in “Journal of Investigative Dermatology” Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
7 citations,
April 1995 in “Endocrinology” Finasteride doesn't affect bone density in male rats.
6 citations,
September 2019 in “Archives of Dermatological Research” Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.
3 citations,
November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
3 citations,
April 1989 in “Drug Information Journal” Side effects of drugs can lead to the discovery of new treatments.
October 2018 in “InTech eBooks” The most effective treatments for hair loss are minoxidil, finasteride, PRP, and hair transplants, with steroids and immunosuppressants for autoimmune types.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” HSD11b1 affects skin nerves and increases non-histaminergic itch.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Astrotactin2 affects hair follicle orientation and skin cell polarity.
451 citations,
March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
434 citations,
October 2003 in “PTR. Phytotherapy research/Phytotherapy research” Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
375 citations,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
374 citations,
May 2016 in “The Lancet. Diabetes & endocrinology” Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
306 citations,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
305 citations,
March 2018 in “International journal of molecular sciences” The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.