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The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Prostaglandin analogs like Latanoprost might help grow hair on the scalp and body.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.

A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

PGF_2α receptors in human eyelids are found in specific parts of hair follicles, explaining eyelash changes with glaucoma treatment.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

Prostaglandin eye drops for glaucoma can rarely cause too much cheek hair growth.

Prostaglandin analogue may help with eyebrow loss in frontal fibrosing alopecia.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

A woman's excessive hair growth around a leg ulcer was linked to a treatment with Prostaglandin E1 ointment.

A woman kept her eyelashes during chemotherapy possibly because of her glaucoma eye drops.

Finasteride may affect male fertility by interfering with specific sperm signaling.

Higher levels of the DP2 receptor may lead to hair loss.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

Blocking a protein called prostaglandin D2 might help treat hair loss.

Prostaglandin E2 collagen matrix may help stimulate hair growth.

Blocking Prostaglandin D₂ may help treat hair loss.

Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.

Bimatoprost treats glaucoma and promotes hair growth, with potential for more medical uses.

Combining TRA and latanoprost is most effective for treating localized alopecia areata.

Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

People with Alopecia areata have higher levels of prostaglandin D2 in their blood and tissues.

HPV infection is linked to better survival in advanced anal cancer, higher radiation doses improve survival, especially in HPV-negative patients, and prostaglandin E₂ pretreatment can protect mouse hair follicles from radiation damage.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.