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Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.

Prostaglandin E2 collagen matrix may help stimulate hair growth.

No cure for female pattern hair loss, but various effective treatments exist.

Alternative treatments show promise for hair growth beyond traditional methods.

Prostaglandins may contribute to male hair loss; targeting them could help treat it.

Topical prostaglandin analogs may help with hair growth but more research is needed.

Conflicting findings in androgenic alopecia are likely due to biopsy location, hair diameter diversity, and hair follicle miniaturization.

Central lipohypertrophy in HIV-infected women may lead to shorter eyelashes.

Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

PRGF treatment is safer and more effective for hair loss than topical minoxidil.

The document concludes that more research is needed to understand hair loss in men and to find new treatments.

Mackerel-derived fermented fish oil helps hair grow by activating growth pathways and increasing cell proliferation.

KY19382 helps regrow hair and create new hair follicles.

CXXC5 is a protein that prevents hair growth and could be a target for hair loss treatment.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.