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Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Targeting CXXC5 and GSK-3β may help treat male pattern baldness.

Targeting the PGD2-DP2 pathway may help treat hair loss.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.

Latanoprostene bunod effectively lowers eye pressure and is better tolerated than other glaucoma medications.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

Certain Dibenzo derivatives may help treat prostate cancer.

Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.

The document concludes that more research is needed to understand hair loss in men and to find new treatments.

Eyelashes are important for looks and eye protection, and more people are treating sparse eyelashes; more research is needed to understand eyelash biology and improve treatments.

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Side effects of drugs can lead to the discovery of new treatments.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.