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New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Estrogen therapy can reduce skin aging but has cancer risks.

Stem cell self-renewal is complex and needs more research for full understanding.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Different types of stem cells and their environments are key to skin repair and maintenance.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Fat cells in the skin help start healing and form important repair cells after injury.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.