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This study found that COL17 deficiency in neonatal mice causes abnormal skin cell proliferation due to disrupted Wnt signaling, while replenishing or overexpressing COL17 can reverse this effect in both neonatal and aged skin.

This study found that VEGF stimulates the proliferation of human hair follicle dermal papilla cells via the VEGFR-2/ERK pathway, without involving p38, JNK, or AKT signaling.

In this study, the researchers found that alopecia in VDR null mice is likely due to issues with hair cycle initiation rather than defects in keratinocyte proliferation or differentiation.

This study found that ginseng-derived nanoparticles promoted skin cell proliferation and facilitated wound healing in a mouse model.

This study identified WNT10A as crucial for adult epithelial cell proliferation and differentiation, suggesting β-catenin pathway activation may help address regenerative defects in WNT10A mutation patients.

This study found that epidermal growth factor significantly enhances the proliferation of hair follicle-derived mesenchymal stem cells through the EGFR/ERK and AKT pathways, without involving the STAT3 pathway.

This study found that iron retention in macrophages impairs hair follicle growth and delays wound healing in mice, highlighting the importance of macrophage iron release for skin health.

This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.

In this study, dihydrotestosterone increased proliferation and decreased IL-6 production in in-vitro fibroblasts from hereditary gingival fibromatosis and normal gingiva, effects partially reversed by anti-androgens.

This study shows that the concentration of epidermal growth factor (EGF) is crucial for determining whether mink hair follicles are promoted or inhibited in vitro, with involvement of the Notch signaling pathway in DP cell proliferation.

This study observed that VEGF165 increases proliferation and migration but alters adhesion properties of cultured human hair follicle cells, indicating a potential role for VEGF/VEGFR-2 in hair follicle regulation beyond angiogenesis.

This study found that the Ovol2-Zeb1 regulatory circuit is crucial for controlling directional migration and proliferation in epithelial cells, facilitating skin regeneration and repair in mice.

This study found that applying TPA to mice accelerated hair follicle regeneration by activating Akt and Wnt/ß-catenin signaling pathways, involving hair follicle stem cell proliferation.

This study found that treating mouse epidermal neural crest stem cells with EGF and FGF2 increased their proliferation and enhanced their neuronal differentiation potential.

This study suggests that alopecia in vitamin D receptor null mice is due to impaired initiation of the hair cycle rather than defects in keratinocyte proliferation or differentiation.

This study demonstrated that the highly divergent WDSV rv-cyclin significantly stimulates eukaryotic cell proliferation, leading to hyperplastic skin lesions in transgenic mice.

This study found that in psoriasis patients, the K17 protein probably functions as an autoantigen, with the HLA-Cw*06:02 risk genotype strongly linked to the T cell response size.

This study found that the SVpgC2a keratinocyte cell line, used as a model for dysplastic epithelium, showed increased apoptosis, proliferation, and aberrant keratin expression compared to normal keratinocytes from buccal mucosa.

This study found that 3-Deoxysappanchalcone may stimulate hair growth in mice by promoting proliferation of hair follicle dermal papilla cells through WNT/β-catenin and STAT signaling modulation.

This study found that PlncRNA‑1 may enhance the proliferation and differentiation of hair follicle stem cells by upregulating the TGF‑β1-mediated Wnt/β-catenin signaling pathway.

This study found that the progesterone metabolite 3α-THP increased the proliferation and gene expression of human glioblastoma cells, suggesting a role in tumor progression.

This study suggests that glycoproteins tenascin-C and tenascin-W may influence the migration and proliferation of CD34-positive stem cells in mouse whisker follicles.

In this study, fluoxetine was found to decrease proliferation and adipogenic differentiation of human adipose-derived stem cells, suggesting it may reduce fat accumulation by increasing autophagy-related gene expression.

This study found that lysophosphatidic acid increases mesenchymal stem cell proliferation and migration through signaling pathways and reactive oxygen species, implicating potential applications in stem cell expansion.

In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.

This study reported that Indian hedgehog (Ihh) signaling plays a crucial role in regulating tumor progression and metastasis in epithelial cancers, with Ihh deficiency leading to increased malignancy and metastasis in mice.

This study found that carvone, a plant-derived compound, decreases melanin content and inhibits melanoma cell proliferation through the cAMP pathway, suggesting potential benefits for treating melanomas and other hyperpigmentation disorders.

This study found that melatonin may enhance goat cashmere growth by activating Wnt signaling and regulating stem cell pluripotency through mechanisms involving NOGGIN and BMP4 pathways.