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Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Melatonin may help treat PCOS symptoms in rats.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Hair microRNAs could be effective biomarkers for diagnosing scleroderma.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Nanoemulsion-based drug delivery systems are versatile and have potential for treating various medical conditions and improving vaccines.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Adrenal disorders can cause lasting brain and behavior issues in children.

Severe vertex pattern hair loss may indicate a higher risk for artery plaque buildup.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.

Human hair follicle dermal cells can effectively replace other cells in engineered skin.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

Signaling pathways are crucial for hair growth in goats.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Fully regenerating human hair follicles not yet achieved.

High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.

The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Dogs could be good models for studying human hair growth and hair loss.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Regenerative therapies show promise for treating vitiligo and alopecia areata.

New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.