31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
9 citations,
August 2022 in “Frontiers in Pharmacology” Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
December 2023 in “Regenerative therapy” miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
5 citations,
February 2022 in “Stem cell reports” Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
1066 citations,
March 2010 in “Nature Reviews Molecular Cell Biology” MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
54 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Disruptions in hair follicle fibroblast dynamics can cause hair growth problems.
February 2024 in “PloS one” Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
October 2020 in “Veterinary Dermatology” New treatments and diagnostic methods for various animal skin conditions showed promising results.
51 citations,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
4 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” Platelet-Rich Plasma (PRP), a protein-rich extract from a patient's blood, shows promise in improving hair density, thickness, and quality, but the best method of use and number of treatments needed for noticeable results are still unclear.
6 citations,
January 2021 in “Journal of the mechanics and physics of solids/Journal of the Mechanics and Physics of Solids” The model shows that factors like follicle shape and stiffness are key for hair growth and anchoring.
1 citations,
April 2023 in “Scientific Reports” Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.
1 citations,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
1 citations,
March 2023 in “Phytochemistry Reviews” CBD may improve skin and hair health, but its effective use and safety need more research.
March 2022 in “Veterinary dermatology” A one-year-old cat had multiple benign skin tumors similar to those known in humans.
1 citations,
October 2001 in “Journal of Wood Science” Some extracts from woods and fungi can promote hair growth better than a known hair growth substance.
42 citations,
February 2014 in “Stem Cells and Development” Vitamin C helps adipose-derived stem cells grow and may support hair growth.
1 citations,
May 2022 in “Frontiers in medicine” Metformin helps improve skin regeneration by increasing the growth of skin stem cells.
33 citations,
August 2013 in “Journal of Investigative Dermatology” Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.
8 citations,
March 2014 in “American Journal of Pathology” Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
384 citations,
June 2005 in “Genes & development” β-catenin is essential for stem cell activation and proliferation in hair follicles.
March 2022 in “Folia Medica Indonesiana” The lump on a woman's scalp was a rare, potentially cancerous tumor from the hair follicle, not a common cyst.
170 citations,
November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
5 citations,
July 2022 in “Genes” Increasing EGR1 levels makes hair root cells grow faster.
11 citations,
January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
6 citations,
July 2023 in “Nature cell biology” SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.
314 citations,
April 2010 in “Developmental Cell” β-catenin in the dermal papilla is crucial for normal hair growth and repair.
45 citations,
July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
April 2018 in “Journal of Investigative Dermatology” The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.