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Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Special fiber materials boost the healing properties of certain stem cells.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Laser device increases hair density, safe for treating hair loss in men and women.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.

Fat cells in the skin help start healing and form important repair cells after injury.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.