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Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.

Key genes and RNAs related to hair growth in sheep were identified, aiding future breeding improvements.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

Targeting colon cancer stem cells might lead to better treatment results.

Notch signalling helps skin cells differentiate and prevents tumors.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

CD2 might be a new treatment target for patchy alopecia areata.

Finasteride may cause long-lasting sexual side effects.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Finasteride affects hair growth by changing caspase and XIAP levels, potentially treating hair diseases.

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.

Sex hormones affect brain injury differently in males and females.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

The FOXN1 gene is crucial for developing immune cells and preventing immune disorders.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Neuregulin3 affects cell development in the skin and mammary glands.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

Chemokine signaling is important for hair development.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Nanotechnology shows promise for better chronic wound healing but needs more research.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.