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No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Adrenal disorders can cause lasting brain and behavior issues in children.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Hair loss requires customized treatments based on its various causes and types.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Minoxidil effectively treats female pattern hair loss.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

Tacrolimus is effective for various skin conditions with fewer side effects than cyclosporine.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Doctors should know how to diagnose and treat PCOS, which often involves checking for high male hormone levels and using medications to manage symptoms.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Finasteride effectively treats male hair loss, improving growth and density.

Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Continuous light exposure in rats leads to PCOS-like symptoms and suggests sleep habits might affect the disorder's development.