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The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

δ-GABAA receptors affect alcohol consumption based on the estrous cycle and influence movement regardless of the cycle.

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.

Anti-androgens can help reduce the effects of male hormones on the skin.

Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Gene mutations can cause problems in male genital development.

Alopecia X in dogs is a cosmetic issue, not a hormonal disorder, and harmful treatments should be avoided.

Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Finasteride reduces movement issues in Parkinson's disease rats.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.

Diagnosing and treating PCOS is complex due to differing criteria and requires a team approach.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.