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Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

Dutasteride may protect the brain in early Parkinson's disease.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

Agmatine may help reduce seizures linked to hormone changes in female rats.

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Androgenetic alopecia, or hair loss, is caused by genetic factors and hormones, with different mechanisms in men and women, and can be linked to insulin resistance and polycystic ovary syndrome.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.

Women with Polycystic Ovary Syndrome (PCOS) have a higher risk of developing type 2 diabetes due to insulin resistance.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.