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Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Hair loss requires customized treatments based on its various causes and types.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Dapsone improved pustular psoriasis in patients who didn't respond to other treatments and is considered a well-tolerated option.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.