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Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Neurosteroids show promise for treating epilepsy and more research is needed.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

New steroids were effective in blocking male hormone receptors in hamster prostates.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

In 2009, there were new medical devices, treatments for gynecological conditions, updated health guidelines, and legal developments in women's health.

Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Gut microbes significantly affect brain steroid levels.