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    Glossary Progenitor Cells

    cells that can differentiate into specific cell types but are more limited than stem cells

    Progenitor cells are a type of cell that has the capacity to differentiate into a specific type of cell but is more limited than a stem cell. Unlike stem cells, which can divide indefinitely and become any cell type, progenitor cells are already on the path to becoming a particular kind of cell and can only divide a limited number of times. They play a crucial role in tissue development and repair, including in the regeneration of hair follicles.

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    1. Equine Hoof Stem Progenitor Cells (HPC) CD29 + /Nestin + /K15 + – a Novel Dermal/epidermal Stem Cell Population With a Potential Critical Role for Laminitis Treatment Stem Cell Reviews and Reports · 2021 · 6 citations
    2. FRI378 Estetrol Prolongs Anagen In Healthy Female Scalp Hair Follicles By Positively Modulating Dermal Papilla Functions And Generation Of Progenitor Stem Cells Ex Vivo Journal of the Endocrine Society · 2023
    3. Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies Journal of Cellular and Molecular Medicine · 2009 · 36 citations
    4. Stem and progenitor cells in sebaceous gland development, homeostasis and pathologies Experimental dermatology · 2021 · 19 citations
    5. Low fucosylation defines the glycocalyx of progenitor cells and melanocytes in the human limbal stem cell niche Stem Cell Reports · 2024 · 3 citations
    6. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014 · 149 citations
    7. Defining microRNA signatures of hair follicular stem and progenitor cells in healthy and androgenic alopecia patients Journal of Dermatological Science · 2020 · 12 citations
    8. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    9. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations Journal of Clinical Investigation · 2011 · 178 citations
    10. Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair Stem Cell Reviews and Reports · 2016 · 24 citations
    11. 699 Effect of Prostaglandin D 2 on hair follicle growth and its impact on hair follicle stem/progenitor cells Journal of Investigative Dermatology · 2016 · 1 citations
    12. 1365 Elf5, a novel regulator of skin stem/progenitor cells fate during skin development? 2023
    13. Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells Journal of Clinical Investigation · 2011 · 235 citations
    14. Anti-aging Properties of Conditioned Media of Epidermal Progenitor Cells Derived from Mesenchymal Stem Cells Dermatology and Therapy · 2018 · 26 citations
    15. Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems Stem Cell Research & Therapy · 2019 · 17 citations
    16. From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis. PubMed · 2021 · 8 citations
    17. TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis The EMBO Journal · 2011 · 91 citations
    18. Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers Journal of Investigative Dermatology · 2013 · 33 citations
    19. Biological Features Implies Potential Use of Autologous Adipose-Derived Stem/Progenitor Cells in Wound Repair and Regenerations for the Patients with Lipodystrophy International Journal of Molecular Sciences · 2019 · 23 citations
    20. Enrichment and characterization of human dermal stem/progenitor cells using collagen type IV Journal of Dermatological Science · 2012 · 11 citations
    21. Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity Stem Cells and Development · 2013 · 10 citations
    22. Characterization of new stem/progenitor cells in skin appendages University of Southern California Digital Library · 2013
    23. 701 Signaling networks between stem cell precursors, transit amplifying progenitors, and their niche in developing hair follicles Journal of Investigative Dermatology · 2016
    24. Isolation of Stem Cells and Progenitors from Mouse Epidermis Current Protocols in Stem Cell Biology · 2017 · 13 citations
    25. Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector Stem Cell Research & Therapy · 2013 · 18 citations
    26. Role of stem/progenitor cells in reparative disorders Fibrogenesis & Tissue Repair · 2012 · 29 citations
    27. Novel in vitro culture condition improves the stemness of human dermal stem/progenitor cells Molecules and Cells · 2013 · 18 citations
    28. Hair growth-promoting effect of human dermal stem/progenitor cell-derived conditioned medium Tissue Engineering and Regenerative Medicine · 2015 · 9 citations
    29. Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion Cancer research · 2012
    30. Deriving Keratinocyte Progenitor Cells and Keratinocytes from Human‐Induced Pluripotent Stem Cells Current protocols in stem cell biology · 2020 · 10 citations