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Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

Exosomes show promise for future tissue regeneration.

TLR2 is important for hair growth and can be targeted to treat hair loss.

Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.

Low-coverage sequencing is a cost-effective way to identify genes related to wool traits in rabbits.

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

CD4+ skin cells may be precursors to basal cell carcinoma.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Tofacitinib may slow hair loss in scarring alopecias but is unlikely to regrow significant hair.

Higher minoxidil dose helps hair growth in non-responders without side effects.

Understanding skin structure and development helps diagnose and treat skin disorders.

Skin aging reflects overall body aging and can indicate internal health conditions.

Future research should focus on making bioengineered skin that completely restores all skin functions.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Different ectodermal organs like hair and feathers regenerate differently, with specific stem cells and signals involved in their growth and response to the environment.

UBM helps hair regrowth in men and women with hair loss.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.

Hair follicle stem cells can turn into many cell types and may help repair nerve damage and have other medical uses.

Stem cell research and regenerative medicine have made significant advancements in treating various diseases and conditions.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Immune cells are crucial for hair growth and preventing hair loss.

Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires various treatments to prevent this.