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The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.

Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Mice with alopecia areata had wider lymphatic vessels in their skin.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

Exosomes could be key in treating skin conditions and healing wounds.

MicroRNAs are crucial for skin development, regeneration, and disease treatment.

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

Human skin xenografting could improve our understanding of skin development, renewal, and healing.

Plet-1 protein helps hair follicle cells move and stick to tissues.

Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.

Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.

WNT signaling is crucial for skin development and healing.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Blocking YAP/TAZ could be a new way to treat skin cancer.

Stem cells from hair follicles in a special gel show strong potential for bone regeneration.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Non-coding RNAs are crucial for skin development and health.

Krt15+ cells in the mouse intestine resist radiation and can start tumors.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Scientists found a new, less invasive way to get stem cells from horse hair for veterinary medicine.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Platelet-rich plasma (PRP) is a simple, cost-effective treatment that promotes hair growth and reduces hair loss, with high patient satisfaction.