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Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

Kaempferol helps skin stem cells grow and may improve skin thickness due to its 3-OH group.

HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.

Integrin β1 is crucial for liver structure and function, preventing fibrosis.

A condition with certain scalp changes may come before acne keloidalis nuchae and other similar hair loss disorders.

A new one-step test can quickly identify skin cancer during surgery.

Topical glucocorticoids thin the skin and change collagen structure.

Cholecystokinin may help reduce skin inflammation in psoriasis.

Higher leptin levels link to hair loss.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Minoxidil affects collagen-related genes, potentially helping treat fibrosis.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.

Bimatoprost increases hair growth in mice without breaking down into other substances.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Different types of skin cells play specific roles in development, healing, and cancer.

Some medicinal plants can help heal wounds and may lead to new treatments.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Skin fat helps with body temperature control and has other active roles in health.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.