50 citations
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December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.
1 citations
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November 2013 in “Pediatrics in Review” This article reviews the management and treatment of acne vulgaris, emphasizing patient education and adherence, but reports no new clinical results; the authors stress the need for individualized therapy.
July 1988 in “Journal of The American Academy of Dermatology” This article reviews therapeutic advances published between December 1986 and December 1987 but reports no new research findings; readers are advised to consult the original articles before considering new therapies.
13 citations
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March 2013 in “International Journal of Cosmetic Science” This study reports that the tetrapeptide AcSDKP significantly promotes skin and hair health in vitro and ex vivo, suggesting it could be used cosmetically to counteract skin aging and hair loss.
7 citations
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August 2009 in “The Journal of Rheumatology Supplement” This study noted that combining oral acitretin with narrowband ultraviolet B therapy may reduce treatment time and dosages for psoriasis, potentially lowering the long-term skin cancer risk.
28 citations
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August 1981 in “Journal of the American Academy of Dermatology” This article discusses the urgent issue of preserving freedom of choice in dermatology, highlighted by the American Academy of Dermatology, and reports no new research findings.
October 2024 in “OBM Transplantation” In this case study, a patient with moderate papulopustular acne showed improvement in acne scars and active lesions after three monthly treatments with autologous plasma-rich growth factors, which help regulate inflammation, inhibit bacterial growth, and restore collagen.
January 2023 in “Journal of cosmetic dermatology” This study found that the synthetic retinoid EC23 effectively induces keratinocyte hyperproliferation and enhances hair growth in mice, showing more potency than all-trans retinoic acid.
4 citations
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February 2025 in “Molecular Medicine” In this study, ALA-PDT significantly reduced lipogenesis in an acne-like model by upregulating OLR1 and suppressing lipid accumulation, highlighting a potential therapeutic target.
March 2024 in “Faculty of 1000 Research Ltd” In this study, researchers at Jawaharlal Nehru Medical College are comparing the effectiveness and side effects of Adapalene gel (0.1%) and Tazarotene gel (0.05%) in acne treatment among patients aged 12-35, with assessments every 4, 8, and 12 weeks. Results are not reported yet.
59 citations
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January 2015 in “Nanoscale” In this study, polymeric micelles containing retinoic acid were found to improve targeted delivery to hair follicle structures in human skin more efficiently than a marketed retinoic acid gel, suggesting potentially safer and more effective acne treatment.
136 citations
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April 2010 in “British Journal of Dermatology” This review discusses guidelines for acitretin use in dermatology, reporting its efficacy in severe psoriasis and recommendations for combination therapies, without providing new clinical trial results.
This study investigates whether adding 30% supramolecular salicylic acid to conventional treatment for mild to moderate acne vulgaris is safe and effective, though specific results are not reported in the abstract.
1 citations
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March 2011 in “Informa Healthcare eBooks” Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.
This study introduces a novel pro-drug formulation of all-trans retinoic acid that reduces skin inflammation and achieves sustained drug release over several days compared to traditional methods.
1 citations
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October 2019 in “مجله كليه طب الكندي” In this study, researchers highlight the role of androgens like dihydrotestosterone in the pathophysiology of acne, pointing to the enzyme 5a-reductase type 1 as potentially more active in individuals with acne, which may contribute to hormonal influences in the condition's development.
3 citations
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January 2016 in “Annals of Dermatology” This article discusses the multifactorial nature of acne, including its association with follicular hyperkeratosis, sebaceous lipids, Propionibacterium acnes, and perifollicular inflammation, but reports no new clinical findings.
5 citations
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February 2025 in “Drug Development Research” This review found that repurposing existing drugs with strong safety profiles may be an effective and cost-efficient strategy to treat acne, although challenges such as regulatory issues and clinical validation remain significant.
November 2025 in “Research Review” This review of studies published after 2020 found that probiotics may significantly reduce acne lesions and improve skin health in individuals with acne vulgaris, though further high-quality research is needed for confirmation and treatment optimization.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
2 citations
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January 2011 in “Elsevier eBooks” This book reviews the various types of acne and acneiform conditions, as well as their treatment options, with expert insights from multiple fields.
February 2023 in “Reactions Weekly” 22 citations
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October 2007 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this case study, combination therapy with dapsone and isotretinoin significantly improved perifolliculitis capitis abscedens et suffodiens, with the patient remaining symptom-free for six months on reduced medication.
This study found that activin B promotes the initiation and development of hair follicles in cultured and neonatal mice.
17 citations
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April 2020 in “Dermatology and Therapy” In this randomized double-blind study, 160 adults with alopecia areata showed significant improvements in hair loss severity after using a bioactive peptide cosmetic product that mimics platelet-rich plasma, while the placebo group showed no significant change, underlining the treatment's potential effectiveness.
January 2024 in “Journal of Dermatology & Cosmetology” This study found that the ThriveCo Anti-Dandruff Pre-Shampoo Treatment, containing ZenscalpinTM, significantly reduced dandruff by 54.79% after 8 days and improved scalp health, with most participants reporting reduced flaking, dryness, and itchiness, and no noted adverse events.
In this study, researchers found that crude extracts from Avicennia marina and its component avicequinone C inhibit mechanisms contributing to androgenic alopecia in vitro, including 5α-reductase activity and DHT-AR interactions, potentially promoting hair growth and delaying the catagen phase in human dermal papilla cells.
This article discusses tretinoin, noting its approved use for acne and photoaging and its broader application in treating various dermatological conditions, but reports no new clinical findings.
April 2026 in “Frontiers in Medicine” In this case report, a female patient with both psoriasis and lichen planus initially responded to acitretin and topical mometasone but experienced a relapse after stopping the treatment. The authors reported marked improvement within 3 months after switching to upadacitinib, aiming to guide clinical decision-making.
5 citations
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January 2024 in “Journal of the American Academy of Dermatology” This study provided 18 evidence-based recommendations for managing acne vulgaris, strongly endorsing treatments like benzoyl peroxide, topical retinoids, and oral isotretinoin for severe cases, and issued conditional recommendations for therapies like salicylic acid and spironolactone, while offering good practice statements on combining treatment methods.