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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

COVID-19 may harm male fertility and damage the reproductive system.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

Hair loss links to high blood pressure, high fat levels, and metabolic issues, suggesting early heart disease screening.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Rat dermal papilla cells have unique genes crucial for hair growth.

Genomic approach finds new possible treatments for hair loss.

Alternative treatments show promise for hair growth beyond traditional methods.

Trichoscopy is useful for diagnosing and monitoring alopecia areata treatment.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

New protein changes may be involved in the immune attack on hair follicles in alopecia areata.

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Some flavonoids may help with hair growth by affecting blood vessel function in hair follicles.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

Bariatric surgery is safe and effective for treating adolescent obesity.

Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.

Ginger supplements helped reduce symptoms and improve metabolic health in hypothyroid patients.