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This study found that the penta-peptide Gly-Pro-Ile-Gly-Ser increased the proportion of thick hair and improved baldness appearance in Japanese men with androgenetic alopecia.

This study suggests that the dipeptide Pro-Ile has FGF18-like activity, can penetrate model human epidermis, and may have potential as a cosmetic ingredient for skin and hair regulation.

Human hair keratin has a 40% α-helix structure that changes to a random coil in 8 M urea.

Crohn's disease can cause hair loss before other symptoms appear.

This study found that deficiency in TLR3/TRIF signaling reduced inflammation and protected mice against postoperative ileus, suggesting potential for TLR3 antagonism as a preventive approach in humans.

This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.

This study examined hair mineral and free amino acid components in various diseases and found that when using effect size analysis, specific components related to diabetes and other conditions were identified, suggesting their potential as novel health indicators.

This study concluded that the CXCL12–CXCR4 signaling pathway significantly contributes to hair loss in androgenetic alopecia and alopecia areata by promoting inflammation and fibrosis, whereas inhibiting this pathway can restore hair growth and follicle health.

This literature review reports that mutations in the SASH1 gene are linked to different pigmentation disorders, including dyschromatosis universalis hereditaria and lentiginosis. It further suggests SASH1's significant role in melanocyte processes and its potential as a target for developing treatments for these conditions.

This review compiles existing knowledge on the mechanisms and diagnosis of various types of hair loss following COVID-19, including telogen effluvium and alopecia areata, and emphasizes the need to educate patients on these conditions.

This study found that transplanting hair follicles into human scars may remodel fibrotic tissue and reduce scarring by altering collagen structure and decreasing pro-fibrotic factors.

This study developed an all-natural hydrogel that promotes diabetic wound healing by converting pro-inflammatory M1 macrophages to anti-inflammatory M2 macrophages in a simple and biosafe manner.

In this study, researchers developed a self-assembling hydrogel called RADA-PDGF2 and found it to accelerate wound closure in a mouse model due to its pro-proliferative and pro-migratory properties, without causing cytotoxicity or immunogenicity.

This study suggests that finasteride treatment may improve pulmonary immune response in mice following trauma and sepsis, indicating potential as a therapeutic option after major trauma.

This review highlights the importance of promptly addressing symptoms in patients with inflammatory bowel disease, whether they stem from disease activity, medication side effects, or related autoimmune conditions, but it reports no new findings.

This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.

This case report describes a young female with pediatric SLE and latent TB who was found to have gastrointestinal tuberculosis, a rarely recognized and often misdiagnosed condition, highlighting the diagnostic challenges and need for early recognition in such cases.

This review highlights the promise of small extracellular vesicles (sEVs) as biomarkers for sepsis, emphasizing their potential to improve early detection and guide therapeutic decisions by reflecting the immune status and pathogen presence in patients.

This review highlights how disruptions in the host microbiome can worsen inflammation and infection-related pathology, while it remains unclear exactly how the microbiome helps resolve such inflammation, potentially impacting future treatments for infection-induced inflammatory diseases.

This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.

This study found that simultaneously inhibiting both KLK5 and KLK7 proteases completely rescued skin barrier defects in a mouse model of Netherton syndrome, suggesting both should be therapeutic targets.

In this study, male-pattern baldness was strongly associated with a higher risk of keratinocyte cancers, particularly squamous cell carcinoma and melanoma, likely due to increased sun exposure on the scalp rather than androgen levels.

The researchers reported that corticosteroid treatments for alopecia areata led to clinical improvement but did not significantly alter oxidative stress markers, suggesting a limited regulatory effect on these systems.

This study found that ureteroileal anastomosis with direct intraluminal visualization had a 4.2% stricture rate, which compares favorably to other techniques with rates between 3.5% and 11.1%.

This case report associates severe zinc deficiency with long-term total parenteral nutrition, suggesting the need for trace element supplementation in such nutritional management.

This study reports an association between the ESR2 gene variant rs10137185 and female-pattern hair loss in German patients.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

This review explores how fluctuations in female sex steroid hormone levels affect periodontal health in women, noting that collaboration between dentists and gynecologists may improve diagnosis and treatment of hormone-related periodontal conditions.

This article discusses tretinoin, noting its approved use for acne and photoaging and its broader application in treating various dermatological conditions, but reports no new clinical findings.