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This study reports that a new protocol using Angio PRP improved wound healing in mice by enhancing key healing processes and regulating inflammation, suggesting potential for clinical advancements.

This study observed that combining PRP with pro-angiogenic cells (Angio PRP) enhanced wound healing in a mouse model by promoting keratinocyte proliferation, angiogenesis, and vessel remodeling.

In this laboratory study, researchers observed that mouse vascular endothelial cells exhibit dynamic changes after exposure to ionizing radiation, including a transient endothelial subpopulation that facilitates vascular-epidermal communication and skin repair, with shifting roles in angiogenesis and immune surveillance over time.

This study found that Grateloupia angusta extract improved wound healing by promoting matrix production and pro-angiogenic activity in cell cultures and enhanced early wound repair in a mouse skin incision model.

This study demonstrated that an aloe polysaccharide-collagen wound dressing improved wound healing by enhancing angiogenesis and reducing inflammation in vivo.

This study found that adipose-derived mesenchymal stem cells produced more anti-inflammatory and pro-angiogenic cytokines on electrospun scaffolds, which enhanced wound healing and macrophage activity in a rat model.

In this study, an immortalized MSC line from human adipose tissue showed potential for applications in regenerative medicine and inflammatory diseases through production of active factors, demonstrated in vitro.

This study found that injecting xeno-free, three-dimensional cell masses from human adipose-derived stem cells improved blood perfusion and preserved limb function in mice without causing tumors or toxicity, suggesting potential for treating severe ischemic diseases.

This review discusses the evolution of adipose tissue research in regenerative medicine, from tissue transfer to cell-free bioengineering applications, highlighting its therapeutic potential, current limitations, and future directions.

This study found that exosomes derived from dental pulp mesenchymal stem cells (DPSC-Exos) significantly promoted hair regrowth and follicle density in a mouse model of androgenetic alopecia, showing similar efficacy to minoxidil by activating pathways that improve follicular vascularization and dermal papilla cell function.

This study observed that using transfected human cord blood cells enhanced skin wound healing in rats by promoting angiogenesis and earlier termination of proliferation compared to untransfected cells.

This study found that in a fluconazole-induced alopecia-like rat model, a 14-day treatment with hypoxia-induced mesenchymal stem cell exosomes significantly increased TGF-β and PDGF levels, which may improve hair growth and suggests a potential therapeutic strategy for alopecia and other inflammation-related skin disorders.

This review discusses advancements in stem cell therapy for cutaneous radiation syndrome, highlighting the potential of various stem cell sources to improve wound healing and reduce symptoms, but reports no new clinical results.

This review summarizes recent research on the therapeutic uses of adipose-derived stem cells for wound healing and treating skin diseases but does not provide new experimental results.

Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.

This study found that human follicle dermal papilla cells promote survival, proliferation, and tubulogenesis of microvascular endothelial cells, highlighting their significant role in hair follicle vascular remodeling.

Androgens reduce hair growth by affecting cell differentiation and blood vessel formation.

This review discusses current experimental research on the use of stem cells, particularly ADSCs and BM-MSCs, in plastic and reconstructive surgery but reports no new clinical findings.

This study found that baicalin promotes human microvascular endothelial cell proliferation, while visnadin and minoxidil enhance tubulogenesis, with hesperidin uniquely increasing VEGFR-2 phosphorylation compared to other compounds tested.

This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.

Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.

This study suggests that topically applied thyroid hormones T3 and T4 promote hair growth on human scalp tissues ex vivo, highlighting potential therapeutic use for hair loss conditions like androgenetic alopecia.

This study found that transplanting human cord blood mononuclear cells transfected with a plasmid encoding VEGF and FGF2 into rat skin wounds may accelerate the wound healing process.

This review discusses the development of electrospun nanofibrous scaffolds for promoting angiogenesis in tissue engineering but notes that their clinical application beyond bone and skin repair is still limited.

In this study, a microneedle patch containing conditioned media from hypoxia-pretreated stem cells enhanced hair regeneration in an androgenetic alopecia mouse model by boosting perifollicular vascularization and hair follicle stem cell activation compared to minoxidil.

This study developed a bilayer bionic skin scaffold that mimics the skin's structure to resist microbial invasion and enhance wound healing, with in vivo animal studies showing improved collagen deposition, neovascularization, and hair follicle formation.

This study found that hMSC secretomes from umbilical cord Wharton's jelly had the most potent angiogenic effects, whereas those from adipose tissue demonstrated the weakest angiogenic potential.

This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.

This study reported that in laboratory conditions, a cell-free supernatant of Bifidobacterium longum BB536 promoted human dermal papilla cell proliferation and reduced damage and apoptosis caused by dihydrotestosterone, suggesting potential use as a preventative treatment for androgenic alopecia by modulating specific signaling pathways.

In this study, researchers found that hypoxic preconditioning significantly improved the regenerative potential of aged adipose-derived mesenchymal stem cells, enhancing their growth, differentiation, and pro-angiogenic capabilities, suggesting a promising strategy for autologous regenerative medicine applications.