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This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.

This review examines the potential mechanisms by which stem cell-derived cell-free therapy may prevent skin aging, highlighting various molecular targets and pathways involved in regeneration, oxidative stress regulation, ECM preservation, cell activity modulation, and inflammation.

This study found significant differences in scalp microbiome composition and volatile organic metabolites between individuals with alopecia areata and healthy controls, suggesting potential microbiome-related therapeutic interventions for hair growth disorders.

This study found that tamsulosin, finasteride use, and aging are significantly associated with increased risk of intraoperative floppy iris syndrome during cataract surgery, while doxazosin does not appear to pose this risk.

This study suggests that the use of finasteride for benign prostate hyperplasia may increase the risk of osteoporosis diagnosis, particularly at higher doses.

This study concluded that the hairless protein interacts with the vitamin D receptor to repress transcription crucial for hair cycling, employing multiple protein interfaces and modulating chromatin structure.

This review analyzes the potential mechanisms by which SARS-CoV-2 may exacerbate symptoms of benign prostatic hyperplasia and suggests a connection via ACE2 and androgen receptor pathways; it reports no new clinical results.

This study found that prostaglandin D2 reduced proliferation in bulge resident K15+ stem cells but not in other K15+ progenitor cells, suggesting differential impacts on hair follicle stem cell niches.

This paper discusses the potential relationship between finasteride's adverse effects and factors like hand preference and sexual orientation, suggesting these could influence risk in male androgenic alopecia treatment, but reports no new clinical results.

In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.

This study found that early-onset baldness in African-American men is associated with an increased risk of developing prostate cancer and more aggressive tumors, with potential interactions involving age and smoking.

In this study, the authors concluded that the VCD-induced follicular depletion rat model can effectively simulate the perimenopause transition, with hormonal changes distinguishing early/mid-transition from late transition to estropause.

Diazepam's effects on anxiety and memory differ between male and female rats due to hormonal influences.

This review proposes a new classification for telogen effluvium, identifying three pathogenetic types with a common feature of profuse hair shedding, but reports no new clinical results.

This study introduces genital sex differentiation parameters (GSDP) to analyze sexual differences in external genitalia and perineum development in mice, revealing varied sensitivity to androgen inhibition in genital structures.

This abstract contains no research findings and pertains only to website navigation and policies.

Advancements in hair keratin research could lead to better hair health treatments.

This study found that combining dibenyline and finasteride for symptomatic BPH treatment offered modest improvements with fewer additional side effects compared to each drug alone.

This case report observed that a selenium-deficient diet in a child with propionic acidaemia led to macrocytosis and hair abnormalities, which improved with selenium supplementation.

This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.

This review summarizes existing reports on placenta extract for treating liver injury and discusses its mechanisms but provides no new clinical results.

In this study, low-dose BPA was associated with induced prostatic hyperplasia in rats, potentially mediated by COX-2 and L-PGDS through pathways involving cell proliferation and apoptosis.

This review discusses the potential mechanisms of platelet-rich plasma in facial rejuvenation and reports no new clinical results, indicating a theoretical basis for its use in tissue regeneration.

This review summarized existing research on finasteride and erectile dysfunction, finding a correlation between finasteride use for benign prostatic hyperplasia and ED, but not strongly for male androgenetic alopecia.

This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.

This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.

This study discusses the proteomic profile associated with hair damage but does not report new experimental findings.

This study found that rare germline pathogenic variants in BRCA2, BRCA1, and ATM are associated with increased risk of aggressive prostate cancer.

In this study, corn silk extract treatment improved symptoms of testosterone-induced BPH by reducing specific mRNA expression and decreasing levels of 5α-R2, DHT, and PSA.

This study found that human placental extract promoted hair growth and influenced cellular pathways in vitro and rat models, suggesting potential for future hair loss treatments.