1 citations
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February 2016 in “Revista Brasileira de Ginecologia e Obstetrícia” This study demonstrated a significant association between high lipid accumulation product (LAP) and hirsutism in women with polycystic ovary syndrome (PCOS).
1 citations
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January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that hypothyroidism in women with PCOS significantly increased insulin resistance and obesity, which might worsen metabolic issues and impact conditions like hair loss and infertility.
1 citations
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January 2016 in “Medicinski glasnik Specijalne bolnice za bolesti štitaste žlezde i bolesti metabolizma” This article discusses congenital adrenal hyperplasia due to 21 hydroxylase deficiency as a cause of ambiguous genitals in 46XX individuals and reports no new research findings.
1 citations
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January 2015 in “Case reports in endocrinology” This case report highlights that women with nonclassical congenital adrenal hyperplasia should be aware of the risk of having a child with classical CAH if their partner also carries a severe mutation.
1 citations
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January 2015 in “Hair therapy & transplantation” This investigation found that certain supplements, particularly whey protein isolate, growth hormones, and anabolic steroids, can negatively impact hair loss by affecting biochemical pathways.
1 citations
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November 2011 in “Open access journal of contraception” This article reviews the role of androgens and oral contraceptives in acne pathogenesis and management but presents no new clinical results.
1 citations
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May 2011 in “Molecular Medicine Reports” This study found no association between the -866G/A polymorphism in the UCP2 gene and the development of polycystic ovary syndrome.
1 citations
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July 2010 in “TURKDERM” This article reviews the impact of psychological factors on skin health and discusses the interplay between stress, the brain, and the immune system but presents no new clinical findings.
1 citations
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April 2009 in “Cochrane Database of Systematic Reviews” This protocol outlines a planned Cochrane Review assessing the effectiveness and safety of treatments for androgenic alopecia in women, reporting no new research findings.
1 citations
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January 2009 in “Cochrane Database of Systematic Reviews” This protocol outlines a planned Cochrane Review to evaluate the effectiveness and safety of treatment options for androgenic alopecia in women, without reporting new findings yet.
1 citations
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January 2009 in “Trepo - Institutional Repository of Tampere University” This study found that vitamin D regulates cholesterol metabolism and may influence prostate cancer development through mechanisms affecting prostate cell growth and sex hormone metabolism.
1 citations
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January 2006 This article reviews the pathophysiology and causes of androgen-mediated hair growth in hirsutism but does not report any clinical outcomes; treatment aspects are discussed separately.
1 citations
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December 1997 in “Journal of The European Academy of Dermatology and Venereology” In this study, 85.9% of 120 hirsute Saudi women exhibited elevated androgen levels, suggesting the need for a comprehensive hormonal evaluation to identify underlying causes of hirsutism.
1 citations
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October 2023 in “Frontiers in endocrinology” This study found that sex hormone-binding globulin promotes facial aging, while sex steroid hormones such as testosterone and estradiol inhibit it, with growth hormone levels showing no significant effect.
1 citations
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March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that Dermal Fibroblast Progenitors have repressed chromatin profiles which hinder their ability to reform skin in allograft assays despite their differentiation potential.
This study found that Plakophilin 1 regulates innate immune responses in keratinocytes by controlling RNA helicase activity, balancing inflammation during epidermal immune challenges.
This review highlights that surface mechanical regulation can program macrophage behavior through specific mechanical cues on material surfaces, potentially advancing immunotherapies and regenerative medicine by enabling precise control over macrophage functions.
December 2025 in “Lviv clinical bulletin” This review found that platelet-rich plasma therapy may enhance ovarian repair and fertility outcomes in ovarian insufficiency, but notes that optimal usage and long-term effects require further investigation.
December 2025 in “International Journal of Research in Dermatology” This consensus highlights that addressing nutritional and endocrine deficiencies through lifestyle modifications, nutritional support, and medical interventions is crucial for managing hair loss associated with endocrine and gynecological disorders, emphasizing the need for a multidisciplinary approach involving dermatologists, nutritionists, endocrinologists, and gynecologists.
November 2025 in “Frontiers in Endocrinology” This review examines the potential of apigenin and ellagic acid as adjunct or alternative treatments for PCOS, but reports no new clinical results and highlights the need for further trials to confirm their efficacy and optimize dosing and delivery.
November 2025 in “International Journal of Clinical Obstetrics and Gynaecology” This study found evidence for a genetic basis of polycystic ovary syndrome, indicating an autosomal dominant pattern of inheritance among first-degree relatives.
October 2025 in “Indian Journal of Physiology and Pharmacology” This case study suggests a potential connection between insulin resistance-induced diabetes and the development of migraine symptoms in a patient with HAIR-AN syndrome, highlighting the importance of early diagnosis and a multifaceted treatment approach.
This review discusses polycystic ovary syndrome, focusing on its primary features of ovulatory dysfunction and hyperandrogenism, and reports no new findings.
August 2025 in “International Journal of Scientific Research in Biological Sciences” In this study, women with polycystic ovarian syndrome were found to have significantly higher blood levels of DHEA, IL-6, and TNF-α compared to healthy controls.
August 2025 in “DS Reviews of Research in Life Sciences” In this study, women with polycystic ovary syndrome showed significantly higher levels of DHEA, IL-6, and TNF-α compared to healthy controls, indicating a possible link between these biomarkers and PCOS.
In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.
March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.
January 2025 in “Ginekologia Polska” In this study, researchers found that certain vitamin D receptor gene polymorphisms are significantly related to insulin concentration during a glucose tolerance test in young women with hyperandrogenism, but these polymorphisms did not affect bone metabolism or other biochemical parameters.
January 2025 in “Exploratory Animal and Medical Research” Among adult male rats, this study found that combined exposure to lithium carbonate and lead acetate over 28 days led to synergistic cardiotoxic effects, evidenced by oxidative stress, ECG abnormalities, and molecular markers of increased apoptosis, despite no observable structural damage to myocardial tissue.
August 2024 in “Frontiers in Pharmacology” This review discusses the potential of therapeutic antibodies as an alternative treatment for androgenetic alopecia, highlighting the initial development stages and the need for further validation and optimization of targets like the prolactin receptor and Interleukin-6 receptor.