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This study observed that beef cattle with certain prolactin receptor gene mutations, known as slick mutations, demonstrated improved post-weaning growth and temperature regulation in a hot, humid climate compared to other genotypes, suggesting genotype influences growth efficiency and heat tolerance.

This study identified several genetic variants associated with cattle hair coat length, which may help breed more heat-tolerant animals by facilitating efficient heat loss.

The study found that prolactin expressed in human scalp hair follicles acts as an autocrine modulator, inhibiting hair growth and promoting hair follicle regression, which may contribute to hair loss in hyper-prolactinemia patients.

This review discusses the effects of hormonal changes on hair follicles, concluding that hormones like androgens and estradiol significantly influence hair growth and cycle, while the roles of other hormones are still being researched.

This article discusses the role of human hair follicles in neuroendocrinology and suggests potential new therapeutic targets by examining how neuromediators influence hair growth, pigmentation, and stem cell biology in organ cultures.

This review discusses the possible impacts of prolactin on skin conditions like psoriasis, alopecia, and stress-related dermatoses, emphasizing the need for further research to explore its therapeutic potential.

This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.

In this study, researchers found that disrupting the PRL gene in mice led to earlier hair molting, especially in females, suggesting that PRL inhibits murine hair cycle events.

This study found that prolactin is a key regulator of keratin expression in human hair follicles, enhancing specific keratin types and influencing epithelial stem cell-associated keratins.

In this study, administrating ovine prolactin accelerated secondary hair follicle reactivation and moulting in cashmere goats, while bromocriptine delayed these processes.

This review discusses prolactin production and regulation in human skin and hair follicles, highlighting its potential broader implications but reports no new empirical results.

This study concluded that an endogenous circannual rhythm of prolactin secretion in mouflon influences their seasonal hair growth and moulting cycle, which varies under different photoperiodic and melatonin treatments.

This article reviews the potential role of prolactin as a neuroendocrine modulator in skin biology and pathology, discussing its relevance for conditions such as psoriasis and hair growth, but reports no new clinical findings.

The researchers reported that in mice, prolactin signaling in the skin epithelium inhibits hair follicle stem cell activation, promoting quiescence during periods of high serum prolactin like pregnancy and lactation.

This review explores potential indications for prolactin receptor inhibitors beyond breast and prostate cancers, emphasizing the need for potent antibodies to further research prolactin receptor expression.

Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.

This study suggests that prolactin has complex, gender- and location-dependent effects on human hair follicles, promoting hair growth in female frontotemporal scalp areas while inhibiting it in male occipital regions.

This study identifies substance P, TNFα, and IFNγ as novel regulators of prolactin and its receptor expression in human skin, suggesting intracutaneous prolactin is not controlled by dopamine.

This study found that placenta-derived mesenchymal stem cells overexpressing PRL-1 inhibited adipogenesis in orbital fibroblasts from Graves’ ophthalmopathy patients by modulating specific signaling pathways, suggesting a potential therapeutic strategy.

This study found that serum prolactin and dehydroepiandrosterone levels did not determine the onset of mink hair growth cycles, though their metabolites may influence other aspects of hair growth.

TSH influences keratin expression in human hair follicles.

This study found that disrupting the PRL gene in mice alters the timing of hair cycling events, causing earlier molts and changes in hair characteristics, particularly affecting female mice more significantly.

This study describes the development of a monoclonal antibody, 005-C04, which blocks PRLR-mediated signaling, suggesting its potential for furthering understanding of PRLR's role in health and disease.

This article discusses the potential of using human hair follicles as a model to study prolactin's regulation and activities but reports no new experimental findings; the authors suggest further research in this area.

This study found that reducing circulating PRL levels is not necessary for the onset of winter hair growth in mink and that adrenal glands do not inhibit this process through DHEA or its metabolite Delta(5)-DIOL.

In this study, 12 months of cyproterone acetate and ethinyl oestradiol treatment significantly reduced hair growth rate and certain hormone levels in hirsute women, though hair density and prolactin levels remained unchanged.

In this study, researchers identified genetic variants in the PCCA and PRLR genes that are significantly associated with hair coat length in Brangus heifers, potentially contributing to more thermotolerant cattle.

In this study, bromocriptine's inhibition of prolactin promoted secondary follicle development during anagen in cashmere goats, likely via changes in specific gene expressions, despite not affecting fiber characteristics or primary follicle activity.

This study found that HRHDT combined with microneedle therapy improved hair growth in a mouse model of alopecia more effectively than microneedle therapy alone.

In this review, the potential role of the hormone prolactin in skin biology and its implications for treating skin diseases and hair disorders are explored, with a focus on its stress-related impacts and possible immunomodulatory function in the context of COVID-19.