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Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.

Low-level Laser Therapy may help reduce inflammation, pain, and aid healing, but more research is needed to confirm its effectiveness and establish standard treatment guidelines.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

The Rotterdam Study aims to understand various diseases in older adults.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Oxidative stress contributes to hair graying and loss as we age.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.