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This review explores the advantages and limitations of using zebrafish models to study various skin diseases, but reports no new experimental results.

This study found that in Hutchinson–Gilford progeria syndrome, iPSCs committed to the keratinocyte lineage faster than normal cells, with LEF1 expression reduced and a partial rescue of the phenotype achieved through adenine base editing.

This review summarizes how single-cell omics technologies have advanced understanding of cellular regulatory programs in sheep and goats, but highlights limitations in genomic annotation and integration with population genetics for molecular breeding.

This review explores the mechanisms, current products, challenges, and innovative approaches related to cosmetics for hair loss prevention and growth promotion, emphasizing the need for multidisciplinary cooperation to enhance product development and market success.

This study reported that a novel cationic liposome formulation for delivering encapsulated Cas9 protein and sgRNA successfully decreased SRD5α2 mRNA expression by 29.7% in vitro, suggesting a potential alternative treatment option for conditions like prostate cancer and benign prostatic hyperplasia without current drug side effects.

This study found that Fgf5 mutant mice exhibited longer hair, particularly in males, likely due to a prolonged anagen phase in the hair cycle.

This review explores emerging therapies for hair regrowth, highlighting two strategies: hair follicle neogenesis and Wnt/B-catenin pathway modulation, which show promise for treating alopecia by potentially offering more effective options than existing treatments.

This study found that 5% primed conditioned medium from human umbilical cord blood-derived mesenchymal stromal cells significantly improved hair density, thickness, and growth rate in patients with androgenetic alopecia.

This review discusses various nanocarriers for gene and genome editing therapies, highlighting that ionizable lipid nanoparticles show advanced delivery performance, while emerging polymer-based and exosome-inspired carriers are rapidly advancing for targeted applications.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

This review explores the role of the TMPRSS2 gene in facilitating SARS-CoV-2 infection and its potential as a therapeutic target in COVID-19 and other respiratory infections, highlighting challenges in developing selective inhibitors.

This review explores current strategies to enhance extracellular vesicle-based delivery of CRISPR/Cas systems, addressing efficiency challenges and suggesting future directions to bridge gene editing technologies with clinical applications.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.

This study concluded that GLCAT14A-C genes are crucial for the function of glucuronic acid transfer to AGPs in Arabidopsis, affecting various growth and reproductive traits such as seed germination and root hair growth.

This review discusses platelet-rich plasma and microneedling in aesthetic medicine, providing a comprehensive literature summary and practical insights, but reports no new clinical results.

This review examines the direct-to-consumer genetic testing market, highlighting the available tests, regulatory issues, and calls for increased oversight, and reports no new results.

In a conditional knockout mouse model, this study found that loss of the transcription elongation factor SPT6 in basal keratinocytes led to psoriasis-like skin inflammation and delayed wound healing, suggesting SPT6 plays a crucial role in maintaining epidermal immune quiescence by suppressing proinflammatory NF-κB signaling.

The book is a valuable, comprehensive guide on hair transplantation, recommended for surgeons and students, with minor areas for improvement.

This review discusses the strategies and potential of CRISPR delivery for gene therapy, highlighting the challenges and innovative use of stimuli-responsive nanocarriers, but reports no new experimental results.

In this study, researchers used the CRISPR/Cas9 system to edit the FGF5 gene in Dorper sheep, observing increased density and finer wool, along with changes in cortisol levels and antioxidant enzyme activity linked to hair follicle development.

This study found that the vitamin D receptor plays a crucial role in hair follicle development in cashmere goats by regulating signaling pathways in dermal papilla cells.

This review discusses how recent advancements in computational and lab-based methods have enhanced peptide drug discovery, noting the efficiency and cost benefits over traditional approaches and the potential for targeting difficult protein interactions, including protein degradation using proteolysis-targeting chimeras.

This narrative review highlights innovations in regenerative medicine and longevity research within plastic surgery, emphasizing biological, ethical, and regulatory aspects. The study underscores the potential to extend healthspans while balancing these advances with ethical considerations and safety.

This editorial discusses the need for continued research on animal fibers, highlighting recent advances in the field and the impact of economic factors favoring meat over fiber production on research volume.

This review discusses strategies to improve CRISPR/Cas systems by addressing limitations like off-target effects and delivery inefficiencies, offering practical guidance and highlighting future applications, but reports no new research findings.

This review examined mechanisms regulating muscle repair, highlighting disruptions in aging and chronic diseases like Duchenne muscular dystrophy and diabetes. It noted that chronic inflammation and metabolic dysfunction hinder effective regeneration and discussed emerging therapies, suggesting multi-target approaches could be promising despite limited clinical evidence.

This study found that adipose-derived mesenchymal stromal cell secretome, particularly when preconditioned with IFNγ, significantly influences cell motility and anti-inflammatory responses, enhancing its potential as a regenerative therapy.

This study introduces a method for long-term expansion of adult mouse epidermal stem cells in vitro using an organoid culture system that maintains the basal-apical organization.

In this study, researchers assessed the genetic diversity of 101 Ginkgo biloba individuals using EST-SSR markers and concluded that there is a high level of genetic diversity in Ginkgo populations, facilitating the construction of a core germplasm collection for breeding purposes.

In this study, the researchers found that over half of the tested calcium food supplements had calcium levels exceeding the amounts declared by their manufacturers, indicating a need for better quality control.