research Skin Manifestations in Primary Immunodeficient Children
Nearly half of children with primary immunodeficiency disorders showed skin problems, often as the first sign of their condition.
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research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research Anatomic Location of Primary Melanoma: Survival Differences and Sun Exposure
Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.
research Prevalence of Alopecia and Its Contributing Factors Among Primary Healthcare Attendees in the Jazan Region, Saudi Arabia
In the Jazan region of Saudi Arabia, hair loss is common, especially among women, older people, and those with higher education and BMI. Stress, poor nutrition, and hormonal changes are key causes, but many don't seek medical help.
research D2-40 Expression in Primary Scarring and Nonscarring Alopecia
Most people with scarring and nonscarring hair loss show similar D2-40 levels, but some with scarring hair loss have higher levels.
research Polycystic Ovary Syndrome: Management of a Long-Term Condition in Primary Care
Manage PCOS in primary care with weight loss, psychological support, medication, and monitoring for health risks.
research Immortalization of Primary Human Dermal Papilla Cells by Bmi-1 and TERT
Hair care products reduced hair roughness, a combination of Stemoxydine and Resveratrol increased hair density, fermented mackerel oil promoted hair growth, and genes TERT and Bmi-1 helped create new hair follicles.
research Dermatological Aspects of Primary Psychiatric Disorders
Psychological issues with skin problems worsen patients' lives and treatment.
research Management of Primary Infertility with Multifactor Etiology - A Case Report
The treatment helped a woman with infertility become pregnant.
research A Rare Primary Subcutaneous Panniculitis-Like T-Cell Lymphoma with Scalp Involvement Associated with Lupus Panniculitis
Repeated biopsies are crucial for managing lupus panniculitis when initial treatments fail.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research Alopecia Areata and Primary Sclerosing Cholangitis
The study concluded that patients with total hair loss and recurring hair loss had an earlier onset, longer-lasting condition, and a greater negative impact on their quality of life, with allergic conditions linked to more severe hair loss.
research Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2
Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.
research Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth
Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.
research Depth and Patterns of Adnexal Involvement in Primary Extramammary (Anogenital) Paget Disease: A Study of 178 Lesions From 146 Patients
Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.
research Safe Selection of Genetically Manipulated Human Primary Keratinocytes with Very High Growth Potential Using CD24
Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.
research Association Between Testicular Microlithiasis and Primary Malignancy of the Testis: Our Experience and Review of the Literature
Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.
research Surgical Atlas: Primary Hypospadias Repair with Buccal Mucosa
Using buccal mucosa for hypospadias repair in children is effective and reduces complications.
research Plant-Derived Biostimulants Differentially Modulate Primary and Secondary Metabolites and Improve the Yield Potential of Red and Green Lettuce Cultivars
Certain natural biostimulants can increase lettuce yield and improve its nutritional content.
research Recent Advances in the Molecular Mechanisms Causing Primary Generalized Glucocorticoid Resistance
Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
research Adult Acne: Prevalence and Portrayal in Primary Healthcare Patients in the Greater Porto Area, Portugal
Many adults in Porto have acne, but few know or treat it.
research Disappearing Foot Disease: An Unusual Presentation of Primary Lymphoma of Bone
An elderly woman's swollen, painful foot was found to be caused by a rare type of bone lymphoma, which improved with radiation treatment.
research A Microscopy-Based Small Molecule Screen in Primary Neurons Reveals Neuroprotective Properties of the FDA-Approved Anti-Viral Drug Elvitegravir
The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.
research Prescription Appropriateness of Cyproterone Acetate/Ethinylestradiol in Primary Care: A Population-Based Study in Italy
The study found that prescribing patterns for Cyproterone Acetate/Ethinylestradiol in Italy did not significantly change after EMA recommendations.
research Recognizing Polycystic Ovary Syndrome in the Primary Care Setting
Doctors should recognize and treat PCOS early in primary care to manage symptoms and lower risk of other health issues.
research Case Report: Extensive Digital Gangrene as a Primary Manifestation of Late-Onset Systemic Lupus Erythematosus
Digital gangrene can be an initial symptom of late-onset systemic lupus erythematosus.
research Investigation and Analysis of 1030 Primary Hair Transplantation Cases: A Retrospective Study
The study found that hair transplant complications are rare, with swelling being the most common issue.
research Using 5 Alpha Reductase Inhibitors Safely: What Primary Care Physicians Need to Know
5 Alpha Reductase Inhibitors (ARIs) are commonly used for conditions like benign prostatic hypertrophy, androgenetic alopecia, and hirsutism. Although they are generally safe, ARIs can cause side effects that may persist even after stopping the medication. This review aims to inform primary care physicians about these common side effects, emphasizing the importance of considering ARIs as a potential cause of new symptoms in patients. This awareness is crucial for accurate diagnosis and management of adverse drug reactions related to ARIs.
research Case Report: Extensive Digital Gangrene as a Primary Manifestation of Late-Onset Systemic Lupus Erythematosus
Digital gangrene can be a rare first sign of late-onset systemic lupus erythematosus.
research Epidermal Renewal After Treatment of Primary Canine Hypothyroidism Using Levothyroxine
Levothyroxine effectively treated a dog's skin and hair problems caused by hypothyroidism.