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Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.

Skin reactions from cancer treatments might predict how well the treatments work.

Scalp cooling effectively reduces hair loss from chemotherapy.

A protein called sFRP4 can slow down hair regrowth.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Effective PCOS treatments require targeting specific signaling pathways.

Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.

A woman with a rare ovarian tumor and hyperparathyroidism improved after surgery, highlighting the need for reporting unusual cases to understand and manage rare diseases.

Neoadjuvant chemotherapy followed by surgery leads to fewer severe complications and better quality of life than immediate surgery in advanced ovarian cancer patients with high tumor load.

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.

Metformin helps improve menstrual irregularities and some hormone levels in PCOS patients, but not symptoms like excess hair, acne, or hair loss.

Managing PCOS effectively requires focusing on psychological health, lifestyle changes, and medication.

The woman's rare combination of diseases suggests an unknown factor may predispose individuals to multiple endocrine diseases.

Certain hair straighteners and dyes may increase ovarian cancer risk, especially in African American/Black women.

Satoyoshi syndrome can occur without causing premature ovarian failure.

A rare, non-cancerous ovarian tumor was successfully treated with surgery, improving the patient's symptoms.

Acupressure improves quality of life in PCOS patients.