research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
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research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Nanostructured Lipid Carriers Loaded with an Association of Minoxidil and Latanoprost for Targeted Topical Therapy of Alopecia
The new treatment using tiny lipid carriers to deliver minoxidil and latanoprost directly to hair follicles shows promise for alopecia.
research Anatomic Location of Primary Melanoma: Survival Differences and Sun Exposure
Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.
research Use of Oral Isotretinoin in the Treatment of Frontal Fibrosing Alopecia: Case Series
Oral isotretinoína effectively stabilizes frontal fibrosing alopecia.
research A New Primary Wound Dressing Made of Polyethylene Oxide Gel
Vigilon, a new wound dressing, promotes faster and better healing with less pain.
research Generalized Glucocorticoid Resistance
Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
research Polycystic Ovary Syndrome: A Review of Cases from General Practice
Most women with polycystic ovary syndrome were first diagnosed by their family doctor, who may need to record symptoms better and rely less on ultrasounds.
research Physical Inactivity Is a Disease Synonymous With a Non-Permissive Brain Disorder
Physical inactivity is a primary cause of many human illnesses.
research Diabetic Foot in Primary Care: A Literature Review
The document concludes that Passiflora incarnata could help with anxiety, telemedicine might improve heart failure care, screen time for kids has increased, pregnant teens in Brazil are mostly okay with their body image, rare tuberculosis infection can occur after knee surgery, older and severely ill people are more likely to have long COVID-19 symptoms, HPLC might diagnose more diabetes cases, and psychiatrists should be involved in pain management.
research Dermatological Aspects of Primary Psychiatric Disorders
Psychological issues with skin problems worsen patients' lives and treatment.
research Role of Tissue Expansion in Hair Restorative Surgery
Tissue expansion is a safe primary method for hair restoration in patients with large scalp defects before hair transplantation.
research Plant-Derived Biostimulants Differentially Modulate Primary and Secondary Metabolites and Improve the Yield Potential of Red and Green Lettuce Cultivars
Certain natural biostimulants can increase lettuce yield and improve its nutritional content.
research Trichoscopy II: Cicatricial Alopecia
Trichoscopy helps tell apart Lichen planopilaris and Frontal fibrosing alopecia from other hair loss conditions.
research Association Between Testicular Microlithiasis and Primary Malignancy of the Testis: Our Experience and Review of the Literature
Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.
research Frontal Fibrosing Alopecia: A Comprehensive Review With Recent Updates
Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.
research Epidermal Renewal After Treatment of Primary Canine Hypothyroidism Using Levothyroxine
Levothyroxine effectively treated a dog's skin and hair problems caused by hypothyroidism.
research Frontal Fibrosing Alopecia
Frontal fibrosing alopecia causes hairline recession and eyebrow loss in postmenopausal women.
research Flap Advancement Technique for Scalp Hair Preservation in Massive Cutis Verticis Gyrata
The flap advancement technique effectively treats severe scalp skin conditions, preserving hair and improving appearance.
research Frontal Fibrosing Alopecia in Men: A Multicenter Study of 39 Patients
Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.
research Efficient Establishment of an Optimized Culture Condition for Cashmere Goat Primary Hair Follicle Stem Cells
Adding Y-27632 and bFGF to the culture medium greatly improves goat hair follicle stem cell growth and quality.
research Contents
Accurate diagnosis and tailored treatment are crucial for managing common primary care symptoms.
research Characterization of Lichen Planopilaris in Men: A Retrospective Analysis
Lichen planopilaris in men often affects the scalp, eyebrows, arms, legs, and beard, with many having family members with hair loss.
research Polycystic Ovary Syndrome, Androgen Excess, and the Risk of Nonalcoholic Fatty Liver Disease in Women: A Longitudinal Study Based on a United Kingdom Primary Care Database
Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
research An Approach to Hair Loss in Hijab-Wearing Individuals in Primary Care
Early diagnosis and treatment of hair loss in hijab-wearing women are crucial to prevent permanent damage and improve quality of life.
research Ingrown Hairs: A Recurrent Trichoscopic Feature in Scarring Alopecias
Ingrown hairs are a common feature in scarring alopecias due to follicular damage.
research The Usual Treatment of Trigeminal Autonomic Cephalalgias
The document concludes that inhalation of oxygen and sumatriptan injections are primary for cluster headaches, indomethacin for paroxysmal hemicrania, and lidocaine and lamotrigine for SUNCT, but SUNCT often resists treatment.
research The Utility of the Classification Tools in National Institute of Health and Clinical Excellence's Clinical Knowledge Summaries for Primary Care
Nearly half of the classification tools in the National Institute of Health and Clinical Excellence's Clinical Knowledge Summaries might not effectively guide management for general practitioners.
research Alternating Hypothyroidism and Hyperthyroidism Complicated by Thyroid Eye Disease
A woman experienced fluctuating thyroid conditions and eye disease, but her symptoms improved with treatment.
research Y27632 Promotes Proliferation via EGFR Signaling in a Newly Isolated and Characterized Human Primary Sebocyte Cell Line
Y27632 increases cell growth through EGFR signaling, not ROCK1/2.