June 2026 in “Journal of Cosmetic Dermatology” CGF-PF may improve hair loss treatment by targeting hair follicle stem cells more effectively.
January 2017 in “Hair transplant forum international” This study examined the effects of platelet-rich plasma (PRP) treatment on women with female androgenetic alopecia in a double-blind, placebo-controlled pilot trial, but specific results were not reported in the abstract.
The project developed and tested a method using plasma rich platelets to treat hair loss.
205 citations
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March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
March 2022 in “Benha Journal of Applied Sciences” This study found that serum PGRN levels and HOMA-IR were significantly higher in male AGA patients compared to controls, suggesting a link to insulin resistance and metabolic syndrome.
June 2025 in “Dermatologic Surgery” This study found that growth factor concentrate provides quicker improvements for patterned hair loss, but platelet-rich plasma offers more sustained benefits after treatment.
3 citations
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September 2022 in “Cureus” This review discusses the various applications of platelet-rich plasma in gynecology but presents no new experimental findings; the authors highlight its potential in managing conditions like Asherman’s syndrome and urinary incontinence.
14 citations
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April 2020 in “Journal of Cosmetic Dermatology” In this study, intradermal injections of QR678 were found to significantly reduce hair fall in men with androgenetic alopecia over 6 months, with superior improvements in hair density and thickness compared to PRP.
96 citations
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October 1987 in “The Journal of Clinical Endocrinology & Metabolism” This study found that long-term GnRH agonist administration in premenopausal women with polycystic ovarian disease resulted in persistent suppression of ovarian steroid secretion, while adrenal steroid levels remained unchanged.
68 citations
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November 2012 in “Journal of Investigative Dermatology” This study found that PGD2 inhibits hair follicle regeneration in mice through the Gpr44 receptor, suggesting that blocking PGD2 or Gpr44 may enhance skin regeneration after wounds.
July 2022 in “Journal of Investigative Dermatology” This review discusses recent clinical trials on the use of platelet rich plasma for treating androgenetic alopecia and reports mixed findings on its effectiveness compared to standard treatments.
7 citations
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August 2020 in “Journal of The American Academy of Dermatology” This letter comments on a randomized controlled trial by Shapiro et al that found no significant benefits of platelet-rich plasma compared to placebo for male androgenetic alopecia, highlighting issues with PRP protocol variations.
March 2026 in “Journal of Ovarian Research” This review explores the potential of platelet-rich plasma therapy for early ovarian reserve decline and premature ovarian insufficiency, indicating some ovarian function improvements in initial studies but highlighting the need for further research.
July 2018 in “Hair transplant forum international” This study observed significant variation in platelet concentrations across four different platelet-rich plasma (PRP) systems, suggesting that PRP system choice may affect treatment outcomes for hair growth.
September 2022 in “Journal of The American Academy of Dermatology” This study found that PRP is most commonly used for treating androgenetic alopecia and facial rejuvenation, with no serious adverse events reported among participants.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This pilot study suggests that a new preparation of platelet-rich plasma gel may improve symptoms and tissue regeneration in patients with en coup de sabre scleroderma, though further trials are needed to clarify its role.
January 2010 in “프로그램북(구 초록집)” 2 citations
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April 2022 in “Der Hautarzt” This review discusses the current literature on platelet rich plasma injections for androgenetic alopecia, noting that while some studies report positive outcomes, they often suffer from methodological weaknesses and inconsistent results.
10 citations
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August 2020 in “Journal of Bioscience and Bioengineering” This study reports that using activated platelet-rich plasma releasate in the preparation of bioengineered hair follicle germs enhanced follicular gene expression and significantly improved hair regeneration in vitro.
19 citations
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January 2017 in “International Journal of Trichology” This study found that a standardized PRP application protocol was effective as a coadjuvant therapy in most patients with androgenetic alopecia who did not respond to minoxidil or finasteride, based on improvements in Ebling's scale.
August 2021 in “Journal of Investigative Dermatology” In this study, activated PRP injections appeared to promote hair growth in AGA-affected scalp skin transplanted onto mice, compared to non-activated PRP.
November 2025 in “PARIPEX-INDIAN JOURNAL OF RESEARCH” GFC is more effective than PRP for treating hair loss.
2 citations
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April 2012 in “Science-business Exchange” Blocking a protein called prostaglandin D2 might help treat hair loss.
April 2019 in “Journal of Investigative Dermatology” The study suggests that variability in platelet-derived growth factors in PRP is influenced by both patient-to-patient differences and the devices used for PRP preparation, contributing to inconsistent clinical outcomes in hair loss treatments.
January 2021 in “Springer eBooks” Combining PRP with other treatments can improve hair loss outcomes.
January 2024 in “Journal of Health Study and Medicine” This review discusses the types, preparation, and current applications of platelet-rich plasma in medicine, particularly focusing on its use in gynecology and obstetrics, but presents no new clinical results.
2 citations
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March 2017 in “Current regenerative medicine” This article reviews the use of platelet rich plasma in regenerative medicine and highlights the need for standardization in its preparation and application, reporting no new clinical results.
16 citations
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May 2000 in “Endocrinology” This study identified a new gene, mrp4, in mice, which suggests it may have a unique role in the growth and development of hair follicles in the ears and tails.
9 citations
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May 2024 in “Cureus” This review discusses the role of platelet-rich plasma in assisted reproductive technology for enhancing endometrial receptivity and reports promising outcomes.
This study presents the G4 transgenic mouse model, which suggests a direct link between polycystic ovary syndrome and the Gm10800 gene, offering a valuable tool for understanding the disease and testing treatments.