56 citations
,
November 2016 in “Aesthetic surgery journal” This review discusses the varied use and inconsistent reporting of platelet rich plasma in aesthetic surgery, finding that current studies lack consistent methodologies and objective evidence, and reports no new clinical results.
55 citations
,
September 2017 in “Journal of Cosmetic Dermatology” This review discusses the diverse applications of platelet-rich plasma in aesthetic dermatology and assesses the existing literature on its effectiveness, reporting no new clinical results.
53 citations
,
June 2017 in “Skin appendage disorders” This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.
47 citations
,
April 2012 in “The Plant Journal” This study found that mutations in phosphorylation sites on the PIN3 protein disrupt its phosphorylation and subcellular trafficking, affecting auxin transport and root growth in a cell-type-specific manner.
46 citations
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February 2012 in “Oncology Reports” This review summarizes existing studies on sorafenib, noting its promising effects in some cancers, but also highlights its limitations and potential synergy when combined with other anticancer treatments.
40 citations
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February 2020 in “Experimental and Therapeutic Medicine” This study found that autologous serum platelet-rich plasma improved skin quality and reduced wrinkles, texture, and pores in healthy females, partly by regulating the expression of MMP-1, tyrosinase, fibrillin, and tropoelastin.
37 citations
,
May 2018 in “Journal of Cosmetic Dermatology” This review analyzed clinical trial protocols for platelet-rich plasma preparation in hair loss treatment, finding inconsistent and insufficient reporting that complicates comparison and efficacy determination.
20 citations
,
July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
20 citations
,
October 2018 in “Aesthetic Plastic Surgery” This review discusses the potential mechanisms of platelet-rich plasma in facial rejuvenation and reports no new clinical results, indicating a theoretical basis for its use in tissue regeneration.
19 citations
,
August 2019 in “Seminars in Plastic Surgery” This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.
18 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.
17 citations
,
May 2023 in “Aesthetic Plastic Surgery” This review found that among emerging technologies for skin anti-aging, stem cell therapies using recipient chimerism might be more beneficial than CRISPR-Cas9 and other current innovations, though further studies on safety and efficacy are needed.
17 citations
,
March 2021 in “Expert Opinion on Biological Therapy” This review analyzes the impact of different preparation methods for platelet-rich plasma, human follicles stem cells, and adipose-derived stem cells on hair regrowth and wound healing, but reports no new results; the authors emphasize convincing evidence of positive outcomes despite protocol variability.
12 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.
11 citations
,
May 2021 in “Dermatologic clinics” This review discusses platelet-rich plasma and cell-based therapies for hair loss, noting promising results but emphasizing the need for standardization and robust trials to confirm their efficacy.
4 citations
,
April 2025 in “Scientific Reports” This study found that platelet-rich plasma can transiently inhibit bacterial growth in vitro against multidrug-resistant strains from diabetic foot infections, although its efficacy diminished over time and did not affect biofilm formation.
2 citations
,
February 2023 in “Shiraz E-Medical Journal” In this study, low-level laser therapy significantly improved the mechanical strength of bone at tooth extraction sites in rats, while neither platelet-rich plasma alone nor combined with laser affected mechanical strength or calcium content.
1 citations
,
October 2023 in “European journal of histochemistry” This study demonstrated that treating platelet-rich plasma with ozone or procaine in vitro led to distinct changes in platelet activity, significantly enhancing the release of platelet-derived factors without damaging the platelets, indicating potential for improved regenerative therapies.
1 citations
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April 2020 in “Plastic and Aesthetic Nursing” This review discusses platelet-rich plasma therapy for nonscarring alopecia and reports no new clinical results; the author recommends more large-scale controlled studies, particularly for scarring alopecia and symptom control.
1 citations
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June 2018 in “Advances in Cosmetic Surgery” PRP might help with hair growth and skin rejuvenation, but more research is needed to prove its effectiveness.
1 citations
,
May 2017 in “InTech eBooks” This review discusses various treatments for noncicatricial alopecias, such as androgenetic alopecia and alopecia areata, including mesotherapy, microneedling, and platelet-rich plasma therapy, noting that outcomes vary across these procedures.
March 2026 in “Editora Pasteur eBooks” This chapter provides a comprehensive review of androgenetic alopecia, covering its key physiological mechanisms, diagnostic methods, and a variety of treatment options ranging from topical therapies to aesthetic and regenerative procedures, emphasizing recent advances observed in dermatological practice.
February 2026 in “Frontiers in Medicine” This review discusses strategies to identify, prevent, and manage complications in FUE and reports no new clinical results.
January 2026 in “Forum Dermatologicum” This article reviews the regenerative benefits of platelet-rich plasma in various medical fields, particularly in dermatology and aesthetic medicine, without presenting new clinical data.
January 2026 in “Biomaterials Science” This research outlines the characteristics and potential applications of a GMP-compliant sodium polyphosphate formulation (Na-polyP-GMP) in cellular energy storage and ATP-dependent processes like skin regeneration and wound healing.
December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.
December 2025 in “Journal of Ovarian Research” This study found that multiple vitamins, including B6, increased the number of growing follicles in newborn mouse ovaries in vitro. VB6 promoted primordial follicle activation via the PI3K/Akt signaling pathway in both cultured mouse and human ovarian tissues.
This review explores psychodermatology and platelet-rich plasma as complementary approaches for enhancing patient-centered care in dermatology, reporting no new results but highlighting their potential to improve outcomes and quality of life.
September 2025 in “Cureus” This narrative review highlights recent advancements in anti-ageing cosmetic procedures, emphasizing personalized interventions that improve patient outcomes and quality of life. The review synthesized evidence from 144 articles to assess the effectiveness and potential side effects of surgical and non-surgical techniques for facial rejuvenation.
September 2025 in “Drug Design Development and Therapy” This study suggests that while platelet-rich products show promise in treating dermatological conditions like chronic wounds and skin aging, there is still a need for standardized methodologies and extensive trials to confirm their long-term clinical benefits.