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Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

The Rotterdam Study aims to understand various diseases in older adults.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Zinc is crucial for growth and health in rats.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.