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A 10-month-old boy with a rare combination of genetic conditions has severe immune deficiency and treatment challenges.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

Epidermolysis bullosa is an inherited condition causing fragile skin with no cure, managed by wound care and experimental treatments show promise.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Hair care products with placental growth factor can improve hair thickness and density in postpartum hair loss.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

Bardet-Biedl syndrome may include under-recognized skin problems related to its metabolic disturbances.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Copper treatments increase copper in all tissues, but brindled female mice accumulate much more copper in their kidneys without clinical effects, unlike brindled male mice where brain copper deficiency is clinically significant.

Finger length ratios don't predict baldness in men.

Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.

Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Taking biotin supplements can be risky and often lacks evidence of effectiveness for skin, hair, and nail issues.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.

The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.

Growth factors greatly affect hair loss, with different levels seen in men, women, younger patients, and at the start of the condition.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Bald men may have a lower risk of testicular cancer.

The severity of symptoms in nonclassical congenital adrenal hyperplasia is not determined by CYP21A2 gene variations.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.