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This study reports that chemically induced short anogenital distance in male rat fetuses involved distinctive transcriptional changes, suggesting roles for estrogen and Wnt2 signaling in anogenital tissue development.

This study found that mice with a mutant CDP/Cux protein lacking the homeodomain showed severely impaired growth, high postnatal mortality, and reduced fertility, highlighting CDP/Cux's role in developmental regulation.

This study found that in vivo, a novel microneedle system for valproic acid delivery may improve hair regrowth efficacy by upregulating hair follicle development pathways more effectively than topical application.

This study suggests that 5α-reduced glucocorticoids may have anti-inflammatory potential and could serve as biomarkers for liver inflammation in metabolic disease, with implications for drug development.

This study suggests that daughters of women with PCOS may have altered androgen metabolism in early childhood, with increased 5α-reductase activity potentially contributing to PCOS development.

This study observed that dietary intake of glucoraphanin during juvenile and adolescent stages prevented cognitive deficits and abnormal gene expressions in the brain of adult offspring exposed to maternal immune activation, potentially implicating centrosome-related genes in the development of psychosis.

This study found that certain endocrine factors, influenced by smoking, birth order, and frequency of orgasms, may play an important role in the development of male breast cancer.

This study found that testosterone and dihydrotestosterone are crucial for synaptic transmission and spine density in male hippocampal neurons, suggesting sex-specific effects of neurosteroids on brain development.

This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.

This study explored the spatial variation of THFD in cashmere goats and identified four genes associated with it, offering insights that could aid in the development of THFD genes for these animals.

This study demonstrated that skin organoids derived from human stem cells can model cutaneous tuberculosis, revealing that fibrosis development in Mycobacterium tuberculosis-infected organoids is linked to the PI3K-AKT and AP1 pathways in fibroblasts, and suggesting the potential for antifibrotic treatment evaluation.

In this study, researchers found that males with alopecia areata had a significantly lower 2D to 4D finger length ratio compared to healthy controls, suggesting this ratio might predict alopecia areata development, though it did not correlate with disease severity.

This study found that neonatal Regulatory T cells are crucial for maintaining PPARγ signaling in hair follicles, which supports melanocyte stem cell function and skin pigmentation during early postnatal development.

This study identified a 582-bp deletion upstream of LHX2 in cashmere goats, likely linked to hair follicle development and cashmere production, providing insights into genetic factors in cashmere trait selection.

This study found that Hoxc13 mutations in mice cause defects in hair, nail, and tongue structures, with the most noticeable issue being brittle hair leading to alopecia.

This study found that Neuregulin3 can influence the development and differentiation of mammary glands and epidermal features in mice, potentially by inducing c-Myc and altering cell proliferation and adhesion.

This article discusses the early development of hair follicles with a focus on the formation of epidermal thickenings called placodes, reporting no new experimental results.

This review outlines the role of mechanical forces in the development of sensory organs like eyes and ears, emphasizing insights from recent animal studies and microfabricated organoid systems; it presents no new experimental results.

In this study, researchers explored ear pinna development in two rodent species and identified that BMP5 plays a crucial role in chondroblast proliferation but not in their initial specification, with implications for understanding tissue differentiation and potential impacts on reconstructive surgery.

Pigs are a good model for studying human hair growth and disorders.

This study found that patients with Bachmann-Bupp syndrome treated with DFMO showed improvements in hair growth, muscle tone, and development.

This paper describes the development of diagnostic criteria for several enduring sexual dysfunction conditions following the use of certain medications, highlighting common sexual and non-sexual symptoms.

This review discusses the role of lncRNA Xist in cell growth regulation and disease development, particularly cancer, and reports no new experimental results.

This study found that sex differences in somatostatin biosynthesis in rat hypothalamic neurons develop between postnatal day 1 and 5, influenced by the conversion of testosterone to estrogen.

This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.

This review highlights the challenges in screening for steroid 5 alpha-reductase inhibitors and discusses significant variability in the effectiveness of finasteride and dutasteride, calling for standardized testing methods to develop safer, more specific inhibitors from herbal preparations.

This study found that WWOX deficiency in mice leads to impaired skin development, reduced epidermal thickness, and significant hypothermia due to disrupted cell proliferation and homeostasis.

This review explores the connection between the gut-skin axis and the development of dermatological conditions like atopic dermatitis, psoriasis, alopecia areata, and acne, and discusses the potential of probiotics in reshaping the microbiome to alleviate these skin issues.

This review outlines the role of testosterone in male sexual development and its therapeutic use for male hypogonadism, covering its biosynthesis, secretion, metabolism, and various biological actions, but does not report specific study results.

This study observed that inhibiting androgenic activity during early postnatal development significantly decreased body weight in female rats by day 90, while affecting food intake and fat distribution in both sexes based on the inhibited testosterone metabolic pathway.