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This chapter reviews genetic defects in female sexual differentiation, focusing on 46,XX disorders of sex development and the impact of genetic factors and sex steroids on development, but reports no new clinical findings.

This study found that lanugo hair appears earlier on the posterior wall of the trunk than on the anterior wall in human fetuses, with a nearly two-week difference in development time.

This review discusses the diverse roles of Frizzled proteins in developmental and homeostatic processes and reports no new experimental findings.

Wnt signaling affects the development and growth of Langerhans cells in mice.

This review examined genetic factors in 46, XY differences/disorders of sex development and found that whole-exome sequencing is more effective than panel sequencing for molecular diagnosis. It identified regional genetic variation and emphasized next-generation sequencing's role in detecting variants related to gonadal and androgen-related genes.

This paper reviews the molecular mechanisms involved in hair follicle development, highlighting their potential impact on human health and well-being, and discusses advancements in treating hair loss, enhancing wound healing, and developing cosmetic treatments.

This source reviews current understanding of fibroblast lineage differentiation and its role in wound healing, highlighting the potential to reprogram adult cells for scar-free repair by emulating fetal-like regenerative states.

This research suggests that autism's genetic links are partially related to factors influencing physiological sex differences, with rare variants interacting with placental sex differences and common variants affecting steroid-related traits.

In this study, a missense mutation in the MAP2 gene was found to be associated with reduced hair follicle density, leading to the hairless phenotype in pigs.

In this study, collagen scaffolds functionalized with heparin and growth factors significantly enhanced long-term skin regeneration and growth in a sheep model of fetal skin defect, suggesting potential for prenatal spina bifida treatment.

This study revealed that deleting EZH2 in mesenchyme-derived cells of the female reproductive tract led to impaired uterine gland development and pregnancy loss in mice, highlighting EZH2's crucial role in fertility.

This review summarizes how single-cell omics technologies have advanced understanding of cellular regulatory programs in sheep and goats, but highlights limitations in genomic annotation and integration with population genetics for molecular breeding.

This study in cashmere goats identified the lncRNA MRPS28, which interferes with secondary hair follicle morphogenesis by inhibiting dermal papilla formation through sponging chi-miR-145-5p, offering insights into breeding strategies for improved cashmere quality.

In this study, maternal melatonin implantation in pregnant rabbits reduced hair follicle cell apoptosis and increased hair follicle density in their neonatal offspring, suggesting a beneficial impact on hair follicle development mediated through specific molecular pathways.

This study found that in neonatal mice, the absence of the NG2 proteoglycan leads to reduced epidermal thickness and delayed subcutis thickening due to impaired proliferation and adipocyte deficiencies.

This review provides a comprehensive guide to the human microbiome and reports no new experimental results; it highlights the impact of modern lifestyles on microbial homeostasis and the necessity of conservation efforts.

The researchers identified a pathogenic variant in the SRD5A2 gene among siblings with 46,XY disorder of sexual development, highlighting the importance of comprehensive genetic testing in diagnosis and management.

This study found that the microRNAs oar-miR-23b and oar-miR-133 inhibit the proliferation and migration of sheep dermal fibroblasts, impacting the development of hair follicles in superfine wool sheep by targeting the genes TGFβ2 and NOTCH1.

This study demonstrated that disrupting sonic hedgehog signaling, using cyclopamine, significantly impaired wound healing in a mouse model, suggesting its crucial role in postnatal tissue repair.

This study reports differential gene expression in the leading edge and inner surface epithelial cells of murine eyelids, suggesting that distinct signaling pathways are active during embryonic eyelid closure.

This study identified novel LSS mutations implicated in hypotrichosis simplex with or without neurodevelopmental abnormalities, highlighting the need for careful evaluation of synonymous mutations' potential pathogenic effects.

In this study, researchers observed monochorionic diamniotic twins with discordant clinical phenotypes, where one had high-grade trisomy 12p mosaicism in certain tissues, while the other showed confined mosaicism likely due to twin-to-twin transfusion.

This review provides a comprehensive overview of apoptosis-related molecules in head development, highlighting caspases' roles and associated abnormalities in tissues like the brain, sensory organs, skin, and bones, without reporting new results.

This study found that early postnatal androgen activity affects the long-term expression of hormone receptors differently in female Wistar rats, influencing neural system programming during development.

This paper summarizes proceedings from a PCOS Special Interest Group, reporting recent advances in the understanding of PCOS follicular abnormalities, associated cardiovascular risks, and dermatological issues, but does not present new clinical findings.

In this study, the misshaped and hairy ear phenotype in mutant mice was linked to mis-expression of certain Hoxc genes due to a chromosomal inversion.

This study found that topical MR blockers alongside glucocorticoids may limit glucocorticoid-induced skin atrophy, suggesting MR's significant role in skin-related endocrinology.

This study found that manipulating maternal cortisol levels during pregnancy altered Merino sheep wool characteristics, increasing fibre length and reducing crimp frequency in the offspring.

This study identified key long non-coding RNAs and mRNAs involved in primary wool follicle induction in carpet wool sheep, emphasizing their roles in hair follicle development and skin processes.

This study found that miR-432 inhibits KRT83 expression, revealing potential molecular mechanisms for the formation of curly fleece in Tan sheep and suggesting implications for understanding curly hair formation in humans.