18 citations
,
December 2006 in “Clinical dysmorphology” This article reviews the case of a 2-year-old boy with rhombencephalosynapsis and considers its potential links to Gomez–López-Hernández syndrome, suggesting further research into its genetic causes; no new clinical results are reported.
6 citations
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January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the complex role of Runx family genes in regulating stem cells in blood and skin tissues and reports no new experimental results.
4 citations
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September 2014 in “Elsevier eBooks” This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.
2 citations
,
October 2022 in “Frontiers in genetics” This case report describes a 46-year-old Italian woman with congenital adrenal hyperplasia who experienced significant improvements in physical and psychological health after receiving a delayed diagnosis and subsequent treatment.
2 citations
,
January 2015 in “Springer eBooks” Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
June 2026 in “Scholarly review .” This review discusses the impact of endocrine-disrupting chemicals on pediatric health, linking them to various disorders, and calls for improved biomonitoring strategies and precautionary policies.
October 2025 in “International Journal of Innovative Research in Technology” This review examines the evidence on nutritional and herbal supplements for women's health, emphasizing the need for more long-term studies to develop evidence-based guidelines for personalized supplementation.
January 2021 in “Research Square (Research Square)” This study found that Wan strain Angora rabbits with high wool production exhibited higher hair follicle density and identified long noncoding RNAs that may regulate this trait.
April 2019 in “Endocrinology and Metabolism Clinics of North America” Inclusive and affirming healthcare is essential for improving transgender individuals' quality of life and health.
June 2018 in “Biomedical Journal of Scientific and Technical Research” In this study, a significant negative correlation was observed between the 2D:4D digit ratio and maxillary sinus volume in men, suggesting an androgenic hormone influence on sinus volume development.
June 2008 in “CRC Press eBooks” PCOS may have evolved as an advantage in past environments with food scarcity.
109 citations
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October 2007 in “American Journal of Human Genetics” This study found that postnatal treatment with recombinant EDA normalized adult teeth, improved sweating, and restored normal lacrimation in dogs with XLHED, suggesting its potential as a treatment for the condition.
47 citations
,
July 2013 in “Pharmacological Reviews” This review discusses the role of pharmacological sciences in advancing regenerative medicine technologies but reports no new experimental findings; the authors advocate for increased pharmacologist involvement to drive innovations.
2 citations
,
December 2014 This review discusses the role of biotin in metabolism and the consequences of its deficiency, reporting no new clinical results.
1533 citations
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October 2008 in “Endocrine reviews” This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
291 citations
,
April 2010 in “Gastroenterology” This study identified Lgr5 and Lgr6 as receptors expressed by small populations of stem cells in various adult organs, with Lgr5+ve cells forming long-lived organoids in certain mouse models.
237 citations
,
February 2016 in “Science Translational Medicine” This study found that many effects previously thought to be caused by circadian rhythm disruption in Bmal1 knockout mice are actually due to BMAL1's properties unrelated to its clock function.
197 citations
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January 2019 in “Neuropsychopharmacology” This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.
158 citations
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May 1968 in “The journal of nutrition/The Journal of nutrition” This study found that severe zinc deficiency induced in weanling rats led to growth retardation, hair issues, and dermal lesions, all of which were completely reversed by zinc supplementation.
71 citations
,
November 2013 in “Clinics in Dermatology” This review discusses the chronic nature of acne and its association with various systemic diseases, but reports no new clinical findings, highlighting the need for further study on its nutritional or genetic links.
60 citations
,
October 2014 in “Journal of the American Academy of Dermatology” This review examines the definition, etiology, pathogenesis, and clinical features of polycystic ovary syndrome but reports no new clinical findings.
56 citations
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April 2015 in “American journal of medical genetics. Part A” This study reports on eight previously unpublished cases of Bohring-Opitz syndrome with ASXL1 mutations, suggesting the importance of screening for Wilms tumors in these patients.
47 citations
,
May 2020 in “Cardiovascular Research” This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.
42 citations
,
April 2013 in “Steroids” This review discusses the pathophysiology, molecular genetics, and management of non-classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency, with no new clinical findings reported.
35 citations
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August 2010 in “The American journal of pathology” This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.
35 citations
,
June 2005 in “The Milbank Quarterly” This article describes a framework for evaluating new health technologies by integrating quantitative evidence with qualitative assessments and using precedents to guide policy decisions, without reporting new clinical results.
29 citations
,
December 2012 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses factors affecting fertility in both men and women with congenital adrenal hyperplasia and emphasizes individualized preconception management but reports no new clinical results.
25 citations
,
March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
18 citations
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September 2021 in “Journal of Neuroendocrinology” This review discusses how neurosteroids acting on GABAA receptors may influence behavior and explores the potential for developing selective modulators for treating psychiatric disorders, but reports no new clinical results.
18 citations
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March 2020 in “Frontiers in Neuroendocrinology” This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.