August 2026 in “International Journal of Pharmaceutical and Clinical Research” This review synthesizes knowledge on HTRA1-associated disorders, highlighting how mutations in the HTRA1 gene are linked to cerebral small vessel disease and systemic conditions, and discusses emerging diagnostic and therapeutic strategies aimed at precision medicine.
June 2026 in “Skin Appendage Disorders” This meta-analysis found that GLP-1 receptor agonists are associated with a 40% increased risk of non-scarring alopecia, likely due to weight loss-induced micronutrient deficiency, with significant associations for telogen effluvium and androgenetic alopecia. However, some patients with central centrifugal cicatricial alopecia showed improvement.
This study found that GLP-1 receptor agonists are linked to a 40% increased risk of non-scarring alopecia in adults, mainly due to weight loss-induced micronutrient deficiencies, with semaglutide and tirzepatide showing the highest hair loss signals.
This study found that GLP-1 receptor agonists are linked to a significant 40% increased risk of non-scarring alopecia, which may result from weight loss-induced micronutrient deficiency.
May 2026 in “Indian Journal of Dermatology” This review provides an overview of genetics, causes, and treatment options for alopecia areata but reports no new clinical results and emphasizes the importance of support for those affected.
May 2026 in “Mayo Clinic Proceedings” This review article connects key systemic lupus erythematosus pathobiology with current therapies, emphasizes clinical strategies for managing comorbidities, and stresses multidisciplinary care, but it reports no new clinical findings.
February 2026 in “Journal of Aesthetic Medicine” This narrative review concluded that facial aging involves complex anatomical changes that require multimodal rejuvenation approaches, integrating fillers, collagen stimulators, botulinum toxin, and energy-based devices for effective results, while emphasizing the need for scientific evidence and patient safety in aesthetic treatments.
January 2026 in “Stem Cell Reviews and Reports” Hair graying may help prevent cancer by protecting stem cells.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review explores the potential benefits of ridge gourd (Luffa acutangula) in promoting hair growth and reducing hair damage through its bioactive components, but emphasizes that further clinical studies are needed to confirm its effectiveness in hair-care products.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights the potential of ridge gourd (Luffa acutangula) in promoting healthy hair growth due to its nutrients and antioxidants, with suggestions of benefits such as follicle strengthening and delaying graying, though it calls for more clinical studies to verify these effects.
November 2025 in “Journal of Investigative Dermatology” A new genetic mutation causing Xeroderma Pigmentosum was found in an 8-year-old girl, affecting her DNA repair.
July 2025 in “Journal of Investigative Dermatology” BrdU speeds up hair follicle aging and reduces hair quality.
June 2025 in “Clinical Cosmetic and Investigational Dermatology” This study examined the factors contributing to gray hair, such as genetics and lifestyle, and found that while graying correlates with some health conditions, it is primarily a physiological process rather than a pathological one.
February 2025 in “International Journal of Molecular Sciences” In this study, researchers identified significant differences in lipid composition between grey and black hair follicles in women with type 2 diabetes and healthy controls, suggesting these lipids may contribute to the production of grey hair and may offer targets for anti-grey-hair treatments.
October 2024 in “Journal of the Endocrine Society” This case report highlights a patient with Ayme-Gripp syndrome, revealing an association between the syndrome and hypothyroidism, and underscores the importance of considering rare genetic conditions in differential diagnoses of endocrinopathies.
July 2024 in “JAAD International” This letter discusses androgenetic alopecia in men and the need for more research to understand its progression with age, reporting no new clinical results.
In this study using a mouse model, researchers utilized single-cell RNA sequencing to create a comprehensive cellular atlas of infected versus uninfected wounds, revealing that Enterococcus faecalis infections lead to immunosuppressive changes in skin cells and disrupt normal wound healing processes.
May 2024 in “International Ayurvedic Medical Journal” The authors of this study detailed the Ayurvedic perspective on hair health, emphasizing holistic approaches like herbal oil massages and dietary changes tailored to individual needs, asserting that such interventions can enhance hair vitality by balancing physiological elements and promoting overall well-being.
May 2024 in “Clinical Cosmetic and Investigational Dermatology” In this study, researchers reviewed the roles of autophagy and mitophagy in hair follicle cycles, exploring their potential links to hair loss and investigating how manipulating these pathways might offer new therapeutic strategies.
February 2024 in “International Journal of Pharmaceutics” This study found that combining the natural product cedrol with minoxidil can improve the treatment of androgenetic alopecia by reducing the minoxidil dose needed, while a new nanocarrier system enhances drug delivery and effectiveness at hair follicles.
February 2024 in “International Journal of Health and Pharmaceutical” In this study, black rice extract ointment was found to enhance hair follicle growth in Wistar rats, with 10% to 30% formulations showing progressively greater hair growth after 21 days, attributed to the high antioxidant content.
January 2024 in “IntechOpen eBooks” This study highlights the various bacterial, fungal, and viral threats to honeybee colonies, such as American Foulbrood and Deformed Wing Virus, and discusses management strategies like Integrated Pest Management and genetic resistance to preserve honeybee populations and their crucial pollination roles.
January 2024 in “International Journal of Trichology” In this study, researchers reviewed the evidence linking COVID-19 with dermatologic conditions like androgenetic alopecia and concluded that most proposed associations lack convincing statistical support, challenging the idea of these as independent risk factors for COVID-19 severity.
This study found that neurosteroids influence oxytocin secretion in sheep, particularly during stress and pregnancy, suggesting their role in protecting and maintaining pregnancy under harmful conditions.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study concluded that KLF4 is a crucial regulator of hair follicle stem cell quiescence and may work by interacting with multiple transcription factors to control related genes.
April 2023 in “Journal of Investigative Dermatology” In ex vivo organ culture of human scalp hair follicles, this study found that IL-9 signaling inhibits hair growth, reduces progenitor cell generation, and disrupts immune privilege.
This study found that simultaneous inactivation of pRb and p53 genes in mice's epidermis accelerates aggressive squamous cell carcinoma development, highlighting p53 as a key tumor suppressor.
This study found that the simultaneous inactivation of pRb and p53 genes in mouse epidermis accelerated aggressive squamous cell carcinoma development via activation of the epidermal growth factor receptor/Akt pathway.
January 2023 in “Social Science Research Network” This case study describes the treatment of a 27-year-old Filipino male with acute patchy hair loss due to alopecia areata, emphasizing the disease's unpredictable progression.
November 2022 in “Journal of Investigative Dermatology” This study reports that activating the bitter taste receptor TAS2R4 with rebaudioside A can inhibit hair growth in human scalp hair follicles by promoting catagen through TGF-β pathway activation.