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Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

DHT affects testicular development and regulates spermatogenesis in some fish.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

Glioblastoma cells can make androgens, which might help the tumor grow.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

Decanoic acid may help treat PCOS by reducing androgen levels and improving glucose sensitivity.

Excess androgens may cause PCOS, not just be a symptom.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Sex hormones affect brain injury differently in males and females.