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More research is needed to understand how testosterone is maintained in adult males.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

Finasteride may protect brain and improve behavior in rats with liver failure.

The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.

The document explains how male reproductive hormones work and affect the body.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Finasteride exposure harms tadpole reproduction and hormone balance.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Older adults use lifestyle drugs to improve life quality and appearance, but caution is needed due to side effects and potential abuse.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

A new mutation in the CYP11B1 gene was found in a woman with mild hyperandrogenemia, a rare cause of non-classic congenital adrenal hyperplasia.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Gut microbes significantly affect brain steroid levels.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

Finasteride doesn't affect ovulation in normal women.