July 1989 in “British Journal of Dermatology” Minoxidil helps increase hair growth and density in people with hair loss, with higher concentrations giving better results.
277 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
229 citations,
August 2002 in “Experimental Gerontology” AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
204 citations,
February 2000 in “Current Medicinal Chemistry” Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
141 citations,
August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
130 citations,
May 1988 in “Journal of The American Academy of Dermatology” "Male-pattern" hair loss is common in women, especially after menopause, and doesn't always mean there's a problem with hormone balance.
112 citations,
July 2008 in “Dermatologic Therapy” Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.
109 citations,
July 1984 in “Circulation” Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.
85 citations,
February 1989 in “Journal of The American Academy of Dermatology” Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.
70 citations,
July 2020 in “Pharmacological Reports” Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
61 citations,
March 1981 in “Circulation” Minoxidil improves blood flow in heart failure patients.
60 citations,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
57 citations,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D receptor is crucial for starting hair growth after birth.
56 citations,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.
53 citations,
January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
52 citations,
May 2017 in “Journal of Cosmetic Dermatology” PRP injections improve hair density and thickness in women with hair loss.
51 citations,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
50 citations,
December 1999 in “British Journal of Dermatology” Finasteride improves hidradenitis suppurativa but not for child-bearing women.
45 citations,
June 2016 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Silicon can improve skin and hair health, but more research is needed.
45 citations,
July 2009 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
44 citations,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
44 citations,
March 1991 in “International Journal of Dermatology” Prompt treatment of inflammatory tinea capitis (kerion) is crucial to prevent scarring and hair loss.
42 citations,
January 2008 in “Dermatology” Dermoscopy effectively distinguishes between acute total hair loss and other types of female hair loss.
34 citations,
October 2012 in “Journal of Dermatology” Growth factors and microneedle therapy increase hair density in women with hair loss.
34 citations,
July 2009 in “Journal of Cell Science” ΔNp63α helps control a protein that stops cancer cells from spreading.
34 citations,
June 1990 in “British Journal of Dermatology” Etretinate treatment changed hair growth patterns in many patients.
34 citations,
October 1982 in “Journal of applied polymer science” Moisture content significantly affects how human hair breaks.
33 citations,
August 1985 in “Archives of Dermatology” Acquired Progressive Kinking of Hair is likely an early sign of male pattern baldness.
30 citations,
December 2017 in “Journal of The American Academy of Dermatology” New criteria for diagnosing frontal fibrosing alopecia include specific scalp and eyebrow hair loss as major factors and other hair loss areas and hair analysis as minor factors.