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Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Hair follicles may soon be used more for targeted and systemic drug delivery.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Tofacitinib may help treat severe hair loss, but more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Finasteride effectively treats baldness but may cause sexual side effects.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

New treatments targeting specific genes show promise for treating keratin disorders.

Choosing the right model order in brain connectivity analysis can affect the detection of differences between healthy individuals and those with seasonal affective disorder.

The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Skin-derived precursors in hair follicles come from different origins but function similarly.