research WNT10B (Wingless-Type MMTV Integration Site Family): Role in Biological Processes and Diseases
WNT10B is linked to cancer development and affects survival and disease progression in various cancers.
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research Is Androgenetic Alopecia Associated With Benign Prostatic Hyperplasia? Analysis of 907 Patients
Hair loss is linked to higher prostate-specific antigen levels and urinary symptoms, likely due to age.
research Genome-Wide Association Study of Fiber Diameter in Alpacas
Certain DNA regions in alpacas are linked to fiber diameter.
research Efficacy of CD101, a Novel Echinocandin, in the Treatment of Dermatophytosis Using a Guinea Pig Model
CD101 is highly effective in treating dermatophytosis in guinea pigs.
research Identifying Molecular Targets for Reverse Aging Using Integrated Network Analysis of Transcriptomic and Epigenomic Changes During Aging
Curcumin may help reverse aging by targeting specific genes.
research Effect of Metformin Using 2-Hour Postload Insulin for Measuring Insulin Resistance in Taiwanese Women with Polycystic Ovary Syndrome
Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.
research Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo
Olorofim effectively treats fungal skin infections.
research Alk1 Acts in Non-Endothelial VE-Cadherin+ Perineurial Cells to Maintain Nerve Branching During Hair Homeostasis
Alk1 in specific cells is crucial for proper nerve branching and hair function.
research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research Saturable Binding of Finasteride to Steroid 5α-Reductase as Determinant of Nonlinear Pharmacokinetics
Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
research Vitamin D3 and Chemotherapy-Induced Alopecia
Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research Cedrol Restricts the Growth of Colorectal Cancer In Vitro and In Vivo by Inducing Cell Cycle Arrest and Caspase-Dependent Apoptotic Cell Death
Cedrol may be an effective treatment for colorectal cancer.
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
research Lineage Analysis of Epidermal Stem Cells
Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
research Structural Requirements of Minoxidil Analogs for Enhancing Lysyl Hydroxylase Inhibitory Activity
Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.
research Transcriptome Reveals Long Non-Coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin
Certain RNA molecules are important for the development of wool follicles in sheep.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
research The Mineralocorticoid Receptor as a Novel Player in Skin Biology: Beyond the Renal Horizon?
The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
research Role of Bulge Epidermal Stem Cells and TSLP Signaling in Psoriasis
Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
research Hair Growth Therapies for Androgenetic Alopecia
Minoxidil, tretinoin, and finasteride may help hair regrowth in mild to moderate androgenetic alopecia.
research A Missense Mutation in Lama3 Causes Androgen Alopecia
A gene mutation in Lama3 is linked to a common type of hair loss.
research Ruxolitinib for the Treatment of Severe Alopecia Areata
Ruxolitinib can help regrow hair in severe alopecia areata.
research Effects of Baicalin on Alopecia and the Associated Mechanism
Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.
research Glutamic Acid Promotes Hair Growth in Mice
Glutamic acid helps increase hair growth in mice.
research Effect of Oil, Water, and Surfactant Mixture on the Physicochemical Properties and Transdermal Delivery of Finasteride-Loaded Microemulsions: Evaluation and Prediction Using Response Surface Methodology
A 3:1 surfactant mixture in microemulsions can effectively deliver finasteride through the skin.
research Plasma Diaphanous Related Formin 1 Levels Are Associated with Altered Glucose Metabolism and Insulin Resistance in Patients with Polycystic Ovary Syndrome: A Case Control Study
Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
research Amendments to Organizational Theorizing
Karl E. Weick recommended focusing on everyday events and smaller organizations to improve organizational theory.
research Amendments to Organizational Theorizing
Karl E. Weick suggested focusing on everyday events and smaller groups to improve organizational theory and urged the inclusion of nonobvious aspects for better explanations.
research Aldo-Keto Reductase (AKR) 1C3 Inhibitors: A Patent Review
The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.