research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
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research The Role of Macrophages in Skin Homeostasis
Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
research DKK1 Mediated Inhibition of Wnt Signaling in Postnatal Mice Leads to Loss of TEC Progenitors and Thymic Degeneration
Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.
research RANK as a Therapeutic Target in Cancer
RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
research Anatomy and Function of the Skin
The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Activating Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Increases Hair Inductivity
Boosting β-catenin signaling in certain skin cells can enhance hair growth.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Morphogenesis and Maintenance of the 3D Thymic Medulla and Prevention of Nude Skin Phenotype Require FoxN1 in Pre- and Post-Natal K14 Epithelium
FoxN1 gene is essential for proper thymus structure and preventing hair loss.
research Age-Related Hair Pigment Loss
Graying hair happens due to aging and might be delayed by new treatments.
research Platelet Factor 4 Inhibits Human Hair Follicle Growth and Promotes Androgen Receptor Expression in Human Dermal Papilla Cells
Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.
research Molecular and Spatial Design of Early Skin Development
The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
research Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules
Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
research Gene Expression Analysis of Chondrogenic Markers in Hair Follicle Dermal Papilla Cells Under the Effect of Laser Photobiomodulation and Synovial Fluid
Laser treatment and synovial fluid can change hair follicle cells to resemble joint cells, with the changes being more significant when both treatments are used together.
research Chemotherapy-Induced Alopecia
Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
research The Chemistry Mechanism of Hair Dyes
Permanent hair dyes use chemicals that react with hydrogen peroxide to create color.
research Epidermal Retinol Dehydrogenases Cyclically Regulate Stem Cell Markers and Clock Genes and Influence Hair Composition
Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
research Tracing Immune Cells Around Biomaterials With Spatial Anchors During Large-Scale Wound Regeneration
Immune cells are essential for skin regeneration using biomaterial scaffolds.
research Schizochytrium Sp. Extracted Lipids Prevent Alopecia by Enhancing Antioxidation and Inhibiting Ferroptosis of Dermal Papilla Cells
Lipids from Schizochytrium sp. help prevent hair loss by protecting hair cells from damage and promoting hair growth.
research Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding
Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.
research Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin
Hair follicles help attract immune cells to the skin during stress.
research Transplantation Immunology: Solid Organ and Bone Marrow
Transplant success has improved with better immunosuppressive drugs and donor matching.
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
research Wnt/β-Catenin Pathway in Tissue Injury: Roles in Pathology and Therapeutic Opportunities for Regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia
The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
research Effects of Nitric Oxide on Skin Burn Wound Healing
Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
research FOXN1 Deficiency: From the Discovery to Novel Therapeutic Approaches
New treatments for immune disorders caused by FOXN1 deficiency are promising.
research CD10 and CD34 in Fetal and Adult Human Hair Follicles: Dynamic Changes in Their Immunohistochemical Expression During Embryogenesis and Hair Cycling
CD10 and CD34 levels change during hair development and different hair growth stages, which could be important for hair regeneration treatments.
research Isolation and Characterization of a Novel Hair Follicle-Specific Gene, Hacl-1
Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
research Effect of Ultraviolet Radiation, Smoking, and Nutrition on Hair
Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.